Publications by authors named "A Abdelgalil"
Background And Aim: Growth factor receptor-bound protein 7 (GRB7) belongs to a group of adaptor proteins characterized by their conserved multidomain structure. These proteins are involved in cellular signaling pathways that regulate cell growth, proliferation, and differentiation. Alterations in GRB7 expression have been linked to multiple human cancers.
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- The study investigated the prevalence and risk factors of extended-spectrum beta-lactamase (ESBL)-producing bacteria in children hospitalized for urinary tract infections (UTIs) at a hospital in Saudi Arabia from 2018 to 2022.
- Out of 242 urine samples analyzed, 20.7% of the isolates were found to be ESBL producers, with previous antibiotic usage and recurrent UTIs identified as significant risk factors.
- The ESBL-producing bacteria showed high resistance rates to ampicillin and third-generation cephalosporins, but were universally sensitive to meropenem, highlighting the need for better antibiotic management in high-risk pediatric cases.
Background/objectives: The purpose of this study was to determine the influence of eradication on the serum level of the orally administered valproic acid (VPA) in children with idiopathic generalized epilepsy; Methods: This prospective cohort observational study included 100 children with idiopathic generalized epilepsy, recruited from a neurology clinic from May 2021 to December 2021. The patients were divided into two groups, each containing 50 children. The first group had a positive stool antigen and -related symptoms, while the second group had a negative antigen.
View Article and Find Full Text PDFBackground: Sciatic nerve repair becomes a focus of research in neurological aspect to restore the normal physical ability of the animal to stand and walk. Tissue engineered nerve grafts (TENGs) provide a promising alternative therapy for regeneration of large gap defects. The present study investigates the regenerative capacity of PRP, ADSCs, and PRP mixed ADSCs on a long sciatic nerve defect (40-mm) bridged by a polyglycolic polypropylene (PGA-PRL) mesh which acts as a neural scaffold.
View Article and Find Full Text PDFOne of the most prevalent disorders of the urinary system is urinary tract infection, which is mostly brought on by uropathogenic Escherichia coli (UPEC). The objective of this study was to evaluate the regenerative therapeutic and antibacterial efficacy of PRP for induced bacterial cystitis in dogs in comparison to conventional antibiotics. 25 healthy male mongrel dogs were divided into 5 groups (n = 5).
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