Publications by authors named "A Abbot"

Introduction: Transcatheter Aortic Valve Implantation (TAVI) techniques gradually evolved since 2002 and have undergone various refinements. Achieving optimal implantation depth has become crucial for good long term outcome. High implantation decreases the likelihood of conduction disturbances.

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Article Synopsis
  • Clopidogrel is commonly used to prevent heart-related issues in patients with coronary artery disease, but its effectiveness can vary due to genetic differences in the CYP2C19 gene, especially among South Asians who are at higher cardiac risk.
  • A study involving 1191 South Asian Indian individuals revealed a genetic link between CYP2C19 variants and acute coronary syndrome (ACS), highlighting that people with certain polymorphisms, like the *2 allele, are at increased risk, while the *17 allele may offer protective benefits.
  • Understanding these genetic influences is crucial for optimizing clopidogrel therapy and improving treatment outcomes for patients in this population.
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Retrieval of a buddy wire following coronary stenting of long, tortuous, and calcified lesions runs the risk of wire entrapment and stent deformation. We report a case of successful percutaneous extraction of a longitudinally deformed coronary stent during retrieval of jailed buddy wire from the left anterior descending artery. ().

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Background: Haematoma expansion due to raised blood pressure in spontaneous intracerebral haemorrhage may determine outcome. The aim of this study was to determine safety and efficacy of lowering blood pressure in acute spontaneous intracerebral haemorrhage.

Methods: This open label, multicentric trial randomized patients ≥18 years with spontaneous intracerebral haemorrhage with no secondary cause within 72 h of onset to tight BP control arm where treatment was initiated if mean arterial pressure (MAP) was ≥115 mm of Hg and conventional BP control arm where treatment was initiated if MAP was ≥130 mm of Hg.

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Contrast-induced nephropathy (CIN) is of concern after the use of radiocontrast media for coronary angiography (CAG) and percutaneous coronary intervention (PCI). We studied the incidence of CIN and its risk factors in patients undergoing CAG. In this prospective study, we included all patients with normal renal parameters undergoing CAG with nonionic radiocontrast media.

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