[The clinical significance of pvuii polymorphism estradiol receptor alpha gene to improve diagnosis of proliferative forms of benign breast dysplasia].

The aim - to determine the role of single nucleotide polymorphism PvuII of the gene EsRα as an indicator of proliferative activity in benign breast dysplasia (BBD) and its effect on receptor status of breast tissue for expression EsRα. Defined genotype PvuII polymorphism EsRα, the expression level in remote EsRα among patients with BBD. For these patients, and morphological parameters samples are divided into groups and compared.

Microinjection of simian adenovirus SA7 (C-8) DNA into the mouse zygotes: differential distribution of viral DNA in organs.

A simian adenovirus SA7 (C-8) DNA was microinjected into fertilized mouse eggs. Thirty-five mice derived from eggs injected with SA7 DNA were screened for the presence of the adenovirus genome in their liver DNA. Eighteen of these mice contained the virus-specific sequences.