[Diagnostic and prognostic significance of the hypoxia-dependent transcriptional mediator for the development of a carious lesion].

Objective: To study diagnostic informational content of change of concentration a hypoxia-inducible factor (HIF-1α) in gingival liquid of patients for assessment of risk of development of carious process.

Material And Methods: 75 patients with the diagnosis dentine caries entered the research: group 1 (n=30) involved patients with primary caries while group 2 (n=45) consisted of patients with caries recurrence in 12 months after treatment.

Results: In all patients HIF-1α was determined in gingival liquid before treatment by the IFA method.

[Hypoxia-dependent control of the activity of innate antimicrobial immunity in patients with dentin caries].

Objective: To study interrelation of maintenance of α-defensins 1-3 and a hypoxia-inducible factor 1-alpha (HIF-1α) in gingival liquid of patients with caries.

Material And Methods: 75 patients with the diagnosis dentine caries were enrolled in the study and divided into two groups: in group 1 (n=30) caries was diagnosed in earlier untreated tooth, the 2nd group (n=45) included patients with the recurrence of carious process (in earlier treated tooth). Controls involved 25 caries-free individuals.

[Clinical and laboratory evaluation of the Elgydium Protection caries toothpaste effectiveness in patients with high intensity of dental caries].

The aim of the work was to evaluate the effectiveness of rehabilitation after the complete elimination of carious cavities in patients with dentin caries according to clinical and laboratory indicators when using the ELGYDIUM Protection caries toothpaste for cleaning teeth for 6 months. 29 patients with high intensity of dental caries were examined and received treatment. Depending on the organization of daily hygienic measures after treatment the patients were divided into two groups.