Personalized treatment is better than one treatment fits all in the management of patients with mCRC: a consensus statement.

The VEGF- (bevacizumab) and EGFR- (cetuximab and panitumumab) targeting monoclonal antibodies have become integral components of the first-line treatment strategies for patients with metastatic colorectal cancer (mCRC). Increasingly combination chemotherapy, with or without a targeted agent, is being used to facilitate curative liver resection and improve survival rates in patients with initially unresectable but potentially resectable mCRC. Currently, the only selective marker for the treatment of patients with mCRC is tumor RAS mutational status.

[Quantitative assessment of the cerebrospinal fluid dynamic parameters in patients with the "benign" intracranial hypertension syndrome. 2].

The development of the benign intracranial hypertensive syndrome was shown to be followed by changes in liquorodynamic parameters and elastic properties of the brain. In 99% of patients, the baseline liquor pressure was elevated by 1.5-2.

[Roentgeno-radiological diagnosis of rhinosinusogenic brain abscesses].

Analysis is made of the data obtained in the use of a complex of diagnostic ++roentgeno-radiological methods in 26 patients with rhinosinusogenous abscesses of the brain. There are convincing examples that the complex (cerebral angiography, gamma-topography of the brain, computer-aided tomography, NMR tomography) enables the identification of the reliable and informative sings of the localization, size, spreading, multiplicity and multicompartmental nature of brain abscesses.

[Magnetic resonance tomography in the diagnosis of paranasal sinusitis].

The potentialities of a new method--magnetic resonance tomography (MRT)--as applied to the diagnosis of paranasal sinusitis are discussed. The method permits detection of inflammation in the paranasal sinuses identified as a significant enhancement of a signal in the projection of the affected sinus. This paper presents two cases: patients with rhinosinusogenic cerebral arachnoiditis and arachnoencephalitis in whom paranasal pathologies which had no clinical manifestations were diagnosed by MRT.

[Lesions of the central nervous system in systemic lupus erythematosus in the computerized-tomographic image].

Computed tomography (CT) of the brain was employed in 40 patients with systemic lupus erythematosus (SLE). Clinical cerebral pathology was obvious in 30 and absent in 10 patients. By CT cerebral symptoms were divided of 4 groups.