Publications by authors named "A A Trofimov"
Article Synopsis
- The review summarizes long-term research by the Saint-Petersburg Institute of Bioregulation and Gerontology on the biological activity of peptide bioregulators and compares findings from domestic and international studies.
- Russian scientists have taken the lead in using buccal epithelium as a diagnostic marker for age-related diseases, highlighting their significant contributions in this field.
- The research reveals that peptides from the epiphysis can enhance melatonin secretion and influence circadian rhythms in the elderly by regulating gene expression and reducing harmful protein synthesis, suggesting their potential as therapeutic agents for age-related issues.
Post-Traumatic Stress Disorder (PTSD) is a multifaceted psychiatric disorder triggered by traumatic events, leading to prolonged psychological distress and varied symptoms. Rat models have been extensively used to explore the biological, behavioral, and neurochemical underpinnings of PTSD. This review critically examines the strengths and limitations of commonly used rat models, such as single prolonged stress (SPS), stress-re-stress (S-R), and predator-based paradigms, in replicating human PTSD pathology.
View Article and Find Full Text PDFLeucine is an essential amino acid that cannot be produced endogenously in the human body and therefore needs to be obtained from dietary sources. Leucine plays a pivotal role in stimulating muscle protein synthesis, along with isoleucine and valine, as the group of branched-chain amino acids, making them one of the most popular dietary supplements for athletes and gym-goers. The individual effects of leucine, however, have not been fully clarified, as most of the studies so far have focused on the grouped effects of branched-chain amino acids.
View Article and Find Full Text PDFA previously unknown class of fluorophores was discovered, which represents 14-membered bridgehead heterocycles, pyrrolyl-diazabicyclo[8.3.1]tetradecadienones, herein referred to as PY-14-ONEs.
View Article and Find Full Text PDFWar is a significant, high-intensity stressor that forces millions of people to seek refuge in safer areas, resulting in profound physical and mental health challenges. Following the large-scale Russian invasion of Ukraine in February 2022, millions of Ukrainians became refugees in Europe. This exploratory study examines the influence of faith on the mental health of Ukrainian forced migrants during the war.
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