Reported transgenerational responses to in are not robust.

Here we report our attempt to replicate reports of transgenerational epigenetic inheritance in . Published results from multiple laboratories show that adults and their F1 embryos exposed to the pathogen show pathogen aversion behavior and a pathogen exposure-dependent increase in reporter gene expression. However, results from one group show persistence of the aversion behavior and elevated expression in the F2, F3, and F4 generations.

Abnormal Liver Biopsies of Donor Grafts in Pediatric Liver Transplantation: How Do They Fare?

BACKGROUND Little is known about outcomes of pediatric patients transplanted using donor liver grafts with abnormal biopsy results. We assessed donor liver biopsy data to report characteristics and outcomes of abnormal livers transplanted in pediatric patients. MATERIAL AND METHODS We identified pediatric patients who received a liver transplant from a biopsied deceased donor between 2015 and 2022 using the national database UNOS Standard Transplant Analysis and Research files.

[Choice of hybrid interventions for iliac-femoral arterial lesions].

Objective: To compare the short-term and long-term outcomes of hybrid interventions after various infrainguinal reconstructions (restoration of blood flow through superficial femoral artery and pulsatile blood flow through deep femoral artery) in patients with iliac-femoral arterial disease.

Material And Methods: A retrospective analysis included patients after hybrid iliac-femoral interventions between 2014 and 2018. These interventions included stenting of iliac arteries and various open infrainguinal reconstructions.

Repulsive Lateral Interaction of Water Molecules at the Initial Stages of Adsorption in Microporous AlPO-11 According to Al NMR and DFT.

Lateral (adsorbate-adsorbate) interactions between adsorbed molecules affect various physical and chemical properties of microporous adsorbents and catalysts, influencing their functional properties. In this work, we studied the hydration of microporous AlPO-11 aluminophosphate, which has an unusually ordered structure upon adsorption of water vapor, and according to Al NMR data, only tetrahedrally or octahedrally coordinated Al sites are present in the AlPO-11. These Al NMR data are consistent with the results of density functional theory (DFT) calculations of hydrated AlPO-11, which revealed the presence of a strong repulsive lateral interaction at the initial stage of adsorption, suppressing the adsorption of water on neighboring (separated by one -O-P-O- bridge) Al crystallographic sites.

A contemporary analysis of 20,086 deceased donor liver biopsies.

Background: Pre-transplant deceased donor liver biopsy may impact decision making; however, interpretation of the results remains variable and depends on accepting center practice patterns.

Methods: In this cohort study, adult recipients from 04/01/2015-12/31/2020 were identified using the UNOS STARfile data. The deceased donor liver biopsies were stratified by risk based on degree of fibrosis, macrovesicular fat content, and level of portal infiltration (low-risk: no fibrosis, no portal infiltrates, and <30% macrosteatosis; moderate-risk: some fibrosis or mild infiltrates and <30% macrosteatosis; high-risk: most fibrosis, moderate/marked infiltrates, or ≥30% macrosteatosis).