Publications by authors named "A A Saryglar"
The Immunological and Epidemiological Effectiveness of Pediatric Single-Dose Vaccination against Hepatitis A 9 to 11 Years after Its Implementation in the Tyva Republic, the Russian Federation.
Vaccines (Basel)
August 2024
Since 2012, universal single-dose HAV vaccination in children aged 3 years and older has been implemented in the Tyva Republic, a region of the Russian Federation. The aim of this prospective non-interventional observational single-center study was to determine the immunological and epidemiological effectiveness of single-dose vaccination against hepatitis A 9 to 11 years after its implementation. The anti-HAV IgG antibodies were determined in two independent cohorts of children who were vaccinated with a single dose of monovalent pediatric inactivated vaccine (HAVRIX 720 EU) in Tyva in 2012 and recruited 9 years (Year 9 Cohort) and 11 years (Year 11 Cohort) after immunization.
View Article and Find Full Text PDFPost-Vaccination and Post-Infection Immunity to the Hepatitis B Virus and Circulation of Immune-Escape Variants in the Russian Federation 20 Years after the Start of Mass Vaccination.
Vaccines (Basel)
February 2023
Article Synopsis
- Russia initiated a neonatal vaccination against Hepatitis B (HBV) 20 years ago, followed by catch-up immunizations for those under 60 starting in 2006, and this study evaluates the immunity and infection rates across different regions.
- Testing of 36,149 volunteers revealed a low HBsAg detection rate of 0.8%, with 2.4% in the Republic of Dagestan, while vaccinated individuals showed less than 0.3% HBsAg detection but a 7.4% rate of ongoing HBV circulation among those under 20 years.
- Despite a stable prevalence of immune-escape HBsAg variants (around 25%), the wild-type HBV population significantly decreased in size
The hepatitis delta virus (HDV) is believed to be a vanishing infection in countries with successful hepatitis B virus (HBV) vaccination programs. We assessed the current status of HDV infection in Tuva, a region of the Russia that has been highly endemic for HBV. The proportion of HDV-infected patients among HBsAg-positive patients in the regional registry in 2020 was 32.
View Article and Find Full Text PDFArticle Synopsis
- * In areas without universal mass vaccination (UMV), seroprevalence has shifted to older age groups, while regions with child vaccination programs saw significant increases in HERD immunity among younger populations.
- * The findings indicate a need for national implementation of UMV, along with strategies to improve vaccination coverage and conduct catch-up campaigns to sustain the effectiveness of existing programs.
Members of the Lipopteninae subfamily are blood-sucking ectoparasites of mammals. The sheep ked () is a widely distributed ectoparasite of sheep. It can be found in most sheep-rearing areas and can cause skin irritation, restlessness, anemia, weight loss and skin injuries.
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