Publications by authors named "A A Samur"
Objective: This study was designed to investigate the relationship between eosinophil count and cardiovascular disease (CVD) in subjects with chronic obstructive pulmonary disease (COPD) and the correlation between eosinophil count and the risk of exacerbations in COPD.
Patients And Methods: The study included 405 patients who met the study inclusion criteria. Of the participants, 100 (25%) were classified as Global Initiative for Chronic Obstructive Lung Disease (GOLD) A, 105 (26%) as GOLD B, and 200 (49%) as GOLD E.
Article Synopsis
- Immunoglobulin M (IgM) multiple myeloma (MM) is a rare condition that needs to be differentiated from other similar diseases, such as Waldenström macroglobulinemia, for effective treatment.
- The study involved analyzing genomic and transcriptomic data of IgM-MM samples through whole-genome and transcriptome sequencing, revealing shared characteristics with MM, but unique features like specific chromosomal translocations and deletions.
- Findings indicated that IgM-MM likely originates before the germinal center stage, highlighted by unique molecular signatures and elevated expression of potential therapeutic targets, such as CD20 and Bruton tyrosine kinase.
Article Synopsis
- The bone marrow (BM) microenvironment is crucial for the development of multiple myeloma (MM), making therapies targeting both cancer cells and their environment effective.
- Recent findings show that mutations in the Roundabout 1 (ROBO1) receptor are common in MM patients, but their role wasn't clear until this study.
- The research reveals that ROBO1 is essential for MM cell adhesion to BM cells, affects tumor growth, and suggests it may have a role in RNA processing, which warrants further investigation.
Introduction: An increase in the incidence of OSAS (obstructive sleep apnoea syndrome) has been seen due to the reported association between OSAS and obesity. Subjects are predisposed to cardiovascular disease due to systemic inflammation caused by the interactions between obesity and OSA. Inflammatory markers could be used to predict the degree of systemic inflammation, which could be a prognostic factor for future adverse events such as metabolic risks.
View Article and Find Full Text PDFIntroduction: To the best of our knowledge, no previous study regarding the serum telomerase levels in Maras powder users (MPUs) has been founded. The aim of the current study was to investigate serum telomerase levels in smokers and MPUs.
Materials And Methods: The study was carried out with 98 patients (36 MPUs, 32 smokers and 30 non-smokers).