Microstructural Alterations of Cerebellar Peduncles in Relapsing Remitting Multiple Sclerosis: a Systematic Review and Meta-Analysis of Diffusion Tensor Imaging Studies.

Damage to cerebellar peduncles is common in patients with relapsing-remitting multiple sclerosis (RRMS). This can lead to a diverse range of motor and cognitive disabilities. Here, we aimed to evaluate the quantitative alterations of cerebellar peduncles using diffusion tensor imaging (DTI).

Microstructural asymmetry in the human cortex.

The human cerebral cortex shows hemispheric asymmetry, yet the microstructural basis of this asymmetry remains incompletely understood. Here, we probe layer-specific microstructural asymmetry using one post-mortem male brain. Overall, anterior and posterior regions show leftward and rightward asymmetry respectively, but this pattern varies across cortical layers.

Validation of the Addenbrooke's Cognitive Examination-III for detecting vascular dementia in Iranian patients with stroke: A secondary data analysis.

The current study was conducted with the aim of evaluating the third version of Addenbrooke's Cognitive Examination (ACE-III), and exploring its diagnostic power for a sample of stroke patients in the Iranian population. This was a cross-sectional analytical study, in which 206 patients with stroke were compared with 200 normal individuals as the control group. The patients were diagnosed based on the findings of neuroimaging and clinical examination by a neurologist.

Bias-accounting meta-analyses overcome cerebellar neglect to refine the cerebellar behavioral topography.

The cerebellum plays important roles in motor, cognitive, and emotional behaviors. Previous cerebellar coordinate-based meta-analyses and mappings have attributed different behaviors to cerebellar subareas, but an accurate behavioral topography is lacking. Here, we show overrepresentation of superior activation foci, which may be exacerbated by historical cerebellar neglect.