Publications by authors named "A A Reza-Albarran"

Article Synopsis
  • Acquired hypophosphatemic osteomalacia (AHO) is a rare bone disorder often caused by phosphaturic tumors that lead to low phosphate levels and poor bone mineralization, with tumor-induced osteomalacia (TIO) being the most common culprit.
  • A study reviewed seven cases of AHO in Peruvian patients between 1999 and 2023, revealing significant diagnostic challenges and varying outcomes; some patients improved after tumor removal, while others did not and even faced fatalities.
  • The findings highlight the necessity for careful diagnosis and treatment planning, as the elusive nature of tumors makes it particularly difficult to manage AHO in regions like Peru with limited medical resources.
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Article Synopsis
  • Diagnosing whether adrenal tumors are malignant or benign can be difficult, especially if both androgens and cortisol are being produced, which raises red flags for malignancy.
  • A 36-year-old woman presented with symptoms like excessive hair growth, an enlarged clitoris, and missed menstrual periods, and imaging revealed a significant adrenal mass and lymph node enlargement.
  • Testing showed high levels of testosterone and cortisol, leading to surgery; pathology confirmed the presence of an adrenal adenoma and a positive PCR for malignancy in the lymph nodes.
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Osteoporosis (OP) is a chronic disease that affects older adults' quality of life, with fragility fractures (FF) being its most significant consequence due to their impact on healthcare systems in terms of morbidity, and economic and caregiving burden. FF are defined as fractures resulting from low-energy trauma, defined as falls from a standing height or less, and are usually considered osteoporotic (1). World demographic projections warn of a significant increase in adults aged 65 and older by 2050.

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Introduction: These guidelines aim to provide evidence-based recommendations for the supplementation of Vitamin D in maintaining bone health. An unmet need persists in Latin American regarding the availability of clinical and real-world data for rationalizing the use of vitamin D supplementation. The objective of these guidelines is to establish clear and practical recommendations for healthcare practitioners from Latin American countries to address Vitamin D insufficiency in clinical practice.

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