Publications by authors named "A A Pogodina"
Article Synopsis
- Glioblastoma (GB) is a highly aggressive brain tumor in adults with complex genetics, making it difficult to treat effectively; current therapies are limited and often ineffective.
- This systematic review, adhering to PRISMA guidelines, analyzed studies from several databases to explore emerging treatments focused on glioblastoma stem cells and advanced drug delivery systems, culminating in 24 eligible peer-reviewed articles from an initial 755 found.
- While the review highlights promising new therapies, it points out limitations like potential language bias, variability among studies, and reliance on preclinical models, emphasizing the need for continuous research in this complex area.
Article Synopsis
- - Trigeminal neuralgia (TN) is a painful condition treated through various surgical methods, including microvascular decompression (MVD) and stereotactic radiosurgery such as Gamma Knife.
- - MVD offers substantial long-term relief but has varying recurrence rates, while GKRS provides good initial pain relief but may require repeat procedures over time.
- - The review stresses the need for personalized treatment plans and careful patient selection to improve outcomes, as each surgical option has its own risks and effectiveness depending on the patient's specific situation.
Adolescence is a critical period for the onset of eating disorders, which affect an adolescent's diet and can have adverse and long-term health consequences. The relationship between the risk of eating disorders and the diet of Russian adolescents has been little studied. of the research was to characterize the relationship between the risk of eating disorders and dietary patterns in a sample of Russian schoolchildren.
View Article and Find Full Text PDFChronic pain affects a substantial portion of the global population, significantly impacting quality of life and well-being. This condition involves complex mechanisms, including dysfunction of the autonomic nervous system, which plays a crucial role in pain perception. The insula, a key brain region involved in pain processing, plays a critical role in pain perception and modulation.
View Article and Find Full Text PDFUnderstanding the principles underlying the stability and sustainability of the gut microbiome of adolescents with normal weight and obesity will make it possible to implement a personalized approach to the correction of metabolic disorders. The article presents the results of a pilot study of the diversity and metabolic potential of the gut microbiome in adolescents with normal body weight and obesity. Biological material was studied using metagenomic sequencing of the V3-V4 variable regions of the 16S rRNA gene.
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