Publications by authors named "A A Podowski"

Background: The popularity of active video games (AVGs) has skyrocketed over the last decade. However, research suggests that the most popular AVGs, which rely on synchronous integration between players' activity and game features, fail to promote physical activity outside of the game or for extended periods of engagement. This limitation has led researchers to consider AVGs that involve asynchronous integration of players' ongoing physical activity with game features.

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Threshold dosages of the photoisomers of cyclodiene insecticides, namely photochlordane, photodieldrin, and photoheptachlor, for the induction of hepatic microsomal cytochrome P450 (P450) and liver hypertrophy in male rats were at least one-quarter of those reported for corresponding parent cyclodienes. Maximum increase in total P450 concentration (30%) and demethylases activities (100%) was always respectively one-third or one-tenth of that reported for parent cyclodienes. The P450 isozymic form induced by photoheptachlor resembled that induced by pentobarbital (P4502B1) in its substrate specificity, spectral characteristics, and electrophoretic mobility.

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Fate of hexachlorocyclopentadiene (Hex) was studied in fresh-water fish using in vivo and in vitro systems. Hex injected intraperitoneally into goldfish is readily distributed, stored and metabolized (greater than 11 organosoluble and hydrophilic metabolites). The body radioactivity in tissues declines, but levels in bile remain high, indicating biliary excretion as a major route of elimination for Hex and its metabolites.

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