Protective Effect of Silver Nanoparticles Against Cytosine Arabinoside Genotoxicity: An In Vivo Micronucleus Assay.

Cancer treatments have harmful side effects, including genotoxic ones. Our previous research discovered that a specific silver nanoparticle (AgNPs) formulation could reduce the genotoxic effects of an alkylating agent, cyclophosphamide. This study aims to evaluate if this protective effect is observed against an antimetabolite anticancer agent, cytosine arabinoside (Ara-C).

Nanobiotechnology for efficient plum pox virus elimination from apricot plants.

Metallic nanoparticles have antimicrobial, virucidal, and anticancer activities and have been widely applied in medicine. In plants, silver nanoparticles have been used as preventive treatments in the greenhouse to reduce viral titers and symptoms. This work investigates the effect of Argovit™ AgNP formulation on apricot plants infected with Plum pox virus or with Hop stunt viroid.

The Influence of Silver-Containing Bionanomaterials Based on Humic Ligands on Biofilm Formation in Opportunistic Pathogens.

The uncontrolled use of antibiotics has led to a global problem of antimicrobial resistance. One of the main mechanisms of bacterial resistance is the formation of biofilms. In order to prevent the growth of antimicrobial resistance, it is crucial to develop new antibacterial agents that are capable of inhibiting the formation of biofilms.

Nanoparticles Partially Restore Bacterial Susceptibility to Antibiotics.

The growing resistance of bacteria to antibiotics is one of the main public health problems nowadays. The influence of silver nanoparticle (AgNP) pretreatment of 220 cows with mastitis on the susceptibility of bacteria to 31 antibiotics was studied. The obtained results were compared with the previous results for , , and .

New Biodegradable Copolymers Based on Betulin and Hydroxycarboxylic Acid Derivatives.

In this study, we propose an approach to the synthesis of new biodegradable polymer materials based on renewable raw feedstock (betulin) and derivatives of hydroxycarboxylic acids using a catalyst/catalytic system (γ-AlO, γ-AlO/TBHP) that is safe for health and the environment. The resulting polymers are linear thermoplastic polymers that undergo collapse upon melting in the presence of atmospheric oxygen. Moreover, these polymers demonstrate non-toxicity towards a range of Gram-positive and Gram-negative bacteria.