Publications by authors named "A A Pawar"

Background: This study evaluates the fracture resistance of apical plugs created from Biodentine and mineral trioxide aggregate (MTA) in thicknesses of 3 and 5 mm within simulated open apex tooth models.

Methods: Fifty human maxillary central incisors were obtained from a pool of freshly extracted teeth. In order to replicate open apices without cavity preparation, ten teeth in the control group received apical-to-coronal preparation with Peeso reamers.

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Article Synopsis
  • Neuron cell processes depend on the interaction of systems like calcium, inositol triphosphate (IP), and dopamine, but studying them individually gives limited insights.
  • A mathematical model was developed to analyze the combined dynamics of these three systems in neurons, incorporating their spatial and temporal behaviors.
  • This model highlights how different cellular mechanisms, such as receptor interactions, affect the dynamics of calcium, IP, and dopamine, and relates these interactions to neurological disorders such as Alzheimer's and Parkinson's disease.
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Myeloid leukemias are heterogeneous cancers with a diverse mutational landscape. Though many mutated genes fall within common protein complexes, some lack known functional partners and have unclear roles. PHF6 is a poorly-understood chromatin-binding protein with recurrent mutations that confer an unfavorable prognosis in acute and chronic myeloid leukemias.

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