EGFR and HER2 expression in cervical cancer patients in Ibadan, Nigeria.

Cervical cancer is a leading cause of cancer-related deaths in developing countries, including Nigeria where it is the second most common female malignancy. Studies from elsewhere have demonstrated the relationship between epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) and advanced cervical cancer. However, we are not aware of such studies in Nigerian patients.

The prevalence and correlates of anxiety and depression amongst essential workers during the COVID-19 lockdown in Ekiti State, Nigeria.

Background: Essential workers are imperative in the fight against the coronavirus disease (COVID-19) pandemic.

Aim: To assess the prevalence and factors associated with anxiety and depression among essential workers during the COVID-19 pandemic and lockdown.

Setting: This study was set in Ekiti State, Nigeria.

The role of radiation treatment in the management of inflammatory musculoskeletal conditions: a revisit.

Inflammatory musculoskeletal conditions are a common group of diseases among the elderly, worldwide. They are characterized by articular degenerative changes accompanied with often debilitating pain. Treatments often involve life-long analgesic therapy or joint replacement in extreme cases.

Determination of extent of PEGylation using denaturing capillary isoelectric focussing.

Conjugated proteins and enzymes are often formed using N-hydroxysuccinimide (NHS) chemistry, which reacts with free primary amines resulting in a loss of charge and a reduction in isoelectric point (pI). Measurement of the extent of reaction of these conjugates is critical for biopharmaceutical developers. Due to this change in protein charge state, denaturing capillary isoelectric focussing (cIEF) offers a potentially straightforward and convenient approach for extent-of-reaction quantification.

RADIOTHERAPY TREATMENT OF KELOIDS IN IBADAN.

Background: The management of keloids has posed a difficult challenge to the patient, surgeon and radiation oncologist due to its high recurrence rate following treatment. Post-operative radiotherapy has been used to improve outcome of treatment by reducing recurrence. However, this is difficult in Africa where there are few Radiotherapy machines and some of those available are not the standard for the treatment for superficial tumours and lesions like keloids.