Publications by authors named "A A Nwankwo"
Article Synopsis
- Red cell distribution width (RDW) is a measure of variability in red blood cell sizes and may indicate cardiovascular disease (CVD) risk, especially in low-resource areas, according to a study in Ghana and Nigeria.
- The study involved 319 adults with hypertension who underwent assessments like blood pressure and RDW measurement, revealing an average RDW of 13.96% and a median CVD risk score of 8.11%.
- Findings showed that RDW is positively correlated with age, systolic and diastolic blood pressure, and WHO CVD risk scores, suggesting RDW could be a useful predictor of CVD risk in this population, particularly with an RDW cutoff of >14
Article Synopsis
- Caesarean scar pregnancy is a rare form of ectopic pregnancy that can lead to serious complications and requires careful diagnosis to improve outcomes.
- A case report details a 35-year-old woman, previously treated for a threatened miscarriage and cervical ectopic pregnancy, who was ultimately diagnosed with a viable Caesarean scar pregnancy at 10 weeks gestation.
- After initial medical treatment with methotrexate and a subsequent surgical procedure, the patient’s condition stabilized, and her pregnancy hormone levels returned to normal following treatment.
Guillain-Barré Syndrome (GBS) is a rare but potentially life-threatening neurological disorder characterized by acute onset ascending paralysis and sensory abnormalities. This article provides a comprehensive overview of GBS, covering its epidemiology, etiology, clinical presentation, diagnostic evaluation, management and treatment, prognosis, psychosocial impact, recent advances in research, public health implications, and ethical considerations. Epidemiological data reveal variations in GBS prevalence, incidence rates, and geographical distribution influenced by climate, infectious disease prevalence, and genetic susceptibility.
View Article and Find Full Text PDFBackground: Gabapentin, a widely prescribed medication for various neuropathic pain conditions, has demonstrated efficacy in managing diverse neurological disorders. While conventional side effects are well-documented, a growing body of evidence suggests the existence of atypical side effects, necessitating comprehensive exploration. This paper aims to systematically review and summarize the literature on the atypical side effects of gabapentin, shedding light on manifestations beyond the conventional spectrum.
View Article and Find Full Text PDFFixed-dose combination (FDC) therapy is recommended for hypertension management in Nigeria based on randomized trials at the individual level. This cluster-randomized trial evaluates effectiveness and safety of a treatment protocol that used two-drug FDC therapy as the second and third steps for hypertension control compared with a protocol that used free pill combinations. From January 2021 to June 2021, 60 primary healthcare centers in the Federal Capital Territory of Nigeria were randomized to a protocol using FDC therapy as second and third steps compared with a protocol that used the same medications in free pill combination therapy for these steps.
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