Publications by authors named "A A Ntorkou"
Background: In juvenile systemic lupus erythematosus (j-SLE) with neuropsychiatric (NP) symptoms, there is a lack of diagnostic biomarkers. Thus, we study whether PET-FDG may identify any metabolic dysfunction in j-NPSLE.
Methods: A total of 19 FDG-PET exams were consecutively performed using PET-MRI system in 11 non-sedated patients presenting with j-NPSLE (11-18y) for less than 18 months (m) and without any significant lesion at MRI.
Article Synopsis
- * A study analyzing 25 ischemic strokes in 1,500 children with SCD from 2007 to 2020 found that 52% had CA, while 48% did not, with older patients more likely to have strokes without CA.
- * The strokes in patients without CA often involved different underlying causes and affected a different demographic, suggesting that long-term transfusion therapy may not be needed for these patients.
Article Synopsis
- Juvenile systemic lupus erythematosus (j-SLE) is a rare autoimmune disease affecting multiple organs, with neuropsychiatric involvement (j-NPSLE) leading to higher morbidity and mortality rates in affected youth.
- *In a retrospective study of j-SLE patients, 44% were diagnosed with j-NPSLE, showcasing common symptoms such as cognitive issues, hallucinations, and mood disorders, with imaging revealing nonspecific brain changes.
- *The study developed a risk score based on clinical features and cerebrospinal fluid analysis to improve the diagnosis and management of j-NPSLE, emphasizing the importance of early recognition and treatment.
Fetal brain imaging provides valuable information in cCMV infected infants.
J Matern Fetal Neonatal Med
December 2023
Background: Congenital CMV infection (cCMV) is the most common congenital infection with 10-15% of cases developing symptomatic disease. Early antiviral treatment is of essence when symptomatic disease is suspected. Recently, the use of neonatal imaging has been implicated as a prognostic tool for long term sequalae among asymptomatic newborns at high risk.
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