Publications by authors named "A A Minkin"

A mutation in is the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Patients with ALS or FTD often develop autoimmunity and inflammation that precedes or coincides with the onset of neurological symptoms, but the underlying mechanisms are poorly understood. Here, we knocked out murine in seven hematopoietic progenitor compartments by conditional mutagenesis and found that myeloid lineage prevents splenomegaly, loss of tolerance, and premature mortality.

View Article and Find Full Text PDF

This study investigated the effectiveness of training geriatric home-based primary care (HBPC) nursing staff in motivational interviewing (MI) techniques, with the goal of increasing patient medication adherence. Nursing staff received 4 hours of training in MI techniques from a licensed psychologist. Results indicated that the MI training increased medication adherence in the HBPC veteran sample by a small, but statistically significant, margin both 1 month and 6 months after the intervention.

View Article and Find Full Text PDF

Aim: To study relationship between coronary reserve and left ventricular geometry.

Method And Material: Transesophageal cardiac pacing was carried out in 53 patients with hypertensive disease. Thirty five patients (66%) had left ventricular hypertrophy which was eccentric in 16 and concentric in 19.

View Article and Find Full Text PDF

Aim: To study effects of pacemaker implantation on the course of coronary heart disease (CHD) with stable angina pectoris and choice of optimal regimen of pacing.

Material And Methods: A total of 154 CHD patients with a pacemaker were examined. All the patients had angina of effort of functional class II-IV.

View Article and Find Full Text PDF

Application of computed (CT) and magnetic resonance tomography (MRT) provided means of precise sitting of tumor and identifying boundaries of adjacent tissue involvement. The study established certain characteristics of CT detection of bone damage. It also showed MRT superiority in visualizing the soft-tissue component of neoplasm and distinguishing between tumor tissue and concomitant secondary inflammation.

View Article and Find Full Text PDF