Publications by authors named "A A Melikian"
[Stereotactic radiosurgery for epilepsy related to hypothalamic hamartoma].
Zh Vopr Neirokhir Im N N Burdenko
August 2022
Unlabelled: Hypothalamic hamartoma (HH) is a dysplastic lesion fused with hypothalamus and followed by epilepsy, precocious puberty and behavioral disorders. Up to 50% of patients become free of seizures after surgery, but various complications occur in 1/4 of cases. Radiofrequency thermocoagulation, laser interstitial thermal therapy and stereotactic radiosurgery (SRS) are alternative treatment options.
View Article and Find Full Text PDFArticle Synopsis
- The study evaluated the impact of endoscopic third ventriculostomy (ETV) and shunting on head circumference and ventricular size in infants with hydrocephalus due to aqueductal stenosis.
- Using data from the International Infant Hydrocephalus Study, researchers analyzed craniometric measurements over a 5-year follow-up period for 158 infants, with 115 receiving ETV and 43 getting shunts.
- Results showed both treatment methods improved head size measurements, with ETV showing better frontal-occipital horn ratio results, although there were no significant differences in overall head circumference between the two procedures.
Aim: To evaluate the efficiency of interferon (IFN) therapy in patients with essential thrombocythemia (ET) and polycythemia vera (PV).
Subjects And Methods: A total of 61 patients (41 with ET and 20 with PV) were examined. Prior to study enrolment, 44 (72%) patients with ET or PV received one or other therapy (aspirin was not taken into account).
Aim: to identify the clinical features of latent polycythemia vera (PV) as an independent nosological entity.
Subjects And Methods: The investigation enrolled 81 patients (50 with extensive (manifest) PV and 31 with latent PV) who had visited the Outpatient Department, Hematology Research Center, Ministry of Health of Russia, in 2014 to October 2015.
Results: The gender distribution of the patients was statistically comparable in the analyzed groups.
Aim: To determine the clinical features of multiple primary tumors (MPT) in patients with hemoblastoses, to develop treatment policy for synchronous and metachronous tumors, and to determine the impact of chemotherapy for one disease on the course and prognosis of another one.
Subjects And Methods: The investigation included 20 patients with multiple primary synchronous and metachronous myeloid and lymphoid tumors, who had been followed up at the Outpatient Department of the Hematology Research Center, Ministry of Health of the Russian Federation. The distribution of patients by nosological entities was as follows: 17 (85%) patients with myeloproliferative diseases (MPDs) concurrent with lymphoproliferative diseases (LPDs) and 3 (15%) with two types of MPD.