The microscopic and ultramicroscopic changes in the skeletal muscles, caused by heavy metal salts.

Purpose: The article is devoted to study the structural changes in the skeletal muscles caused by heavy metal salts.

Materials And Methods: The study was conducted on 72 mature male rats. The experimental groups were given to drink water with combinations of heavy metal salts for one, two and three months.

[Metabolism in experimental chronic ischemic heart disease].

An increase in frequency of heart contractions, changes in the bioelectrical heart activity and decrease of the force-pump heart function are observed in the rabbits with model chronic ischemic heart disease lipid metabolism in significantly changed the concentration of cholesterol in the right ventricle myocardium as well as the concentrations of unsaturated lipid acids in the heart tissues increase, while the content of saturated lipid acids and antioxidant activity of plasma decrease. Bioenergetic processes change as follows: succinate-dehydrogenase and alpha-keto-glutarate-dehydrogenase activity decrease, while the concentrations of glycogen, lactic and pyruvic acids and lactate dehydrogenase activity in the heart tissues increase.

[The relation between oxidative processes and the glycogen content in the heart and liver of rabbits with chronic ischemic heart disease].

While laboratory experimental model of coronary heart disease (according to Frol'kis et al.) is developed, activity of succinate dehydrogenase, alpha-ketoglutarate dehydrogenase, Na+, Ka(+)- and Mg2+ ATPase decreases, but activity of lactate dehydrogenase and concentrations of lactic and pyruvic acids in the heart tissue increase. At the same time concentration of glycogene increases more than twice.

[Toxicological and hygienic evaluation of water obtained by the method of hydration of carbon dioxide].

The irritating, sensitizing, and toxic effect of water produced by the method of carbon dioxide hydration was examined in animal experiments and human observations. It was found that before and after decontamination this water did not cause skin irritation or organism sensitization, did not have a toxic effect on the CNS, liver, kidneys or blood morphology, and did not deteriorate adaptive capabilities of the animal or human body.

[Hygienic evaluation of electrolysis oxygen obtained from the water of different chemical composition].

Influence of electrolysis gaseous oxygen (EGO) mixed with nitrogen (1:4) on the living organism was studied in a 30-day 24-hour experiment on guinea pigs. A preliminary conclusion states, that EGO, obtained in the system with a solid polymeric electrolyte out of moist materials of different chemical composition, can be recommended for the formation of artificial gas atmosphere in hermetic objects in the mixture with gaseous nitrogen in the ratio 1:4.