Publications by authors named "A A Malayeri"
Purpose: Hereditary pheochromocytomas and paragangliomas can be associated with mutations in the mitochondrial enzyme succinate dehydrogenase. Due to their heterogenous clinical presentation, no clear universal screening guidelines are currently available. We sought to examine the utility of metabolic testing and imaging in diagnosing hereditary pheochromocytomas and paragangliomas.
View Article and Find Full Text PDFBackground: Cell-free DNA (cfDNA) sequence analysis to screen for fetal aneuploidy can incidentally detect maternal cancer. Additional data are needed to identify DNA-sequencing patterns and other biomarkers that can identify pregnant persons who are most likely to have cancer and to determine the best approach for follow-up.
Methods: In this ongoing study we performed cancer screening in pregnant or postpartum persons who did not perceive signs or symptoms of cancer but received unusual clinical cfDNA-sequencing results or results that were nonreportable (i.
Article Synopsis
- * A study analyzed the locations of 160 sarcomas found in individuals with LFS and discovered that abdominal sarcomas and extremity osteosarcomas were the most common, with no significant differences based on age or sex.
- * The findings indicate that while sarcomas in LFS often appear in typical areas, they can also occur in unusual locations, complicating diagnosis through imaging; ongoing research will improve guidance for screening and interpretation of scans for LFS patients.