Computational Binding Analysis of Ethyl 3,3,5,5-Tetracyano-2-Hydroxy-2-Methyl-4,6-Diphenylcyclohexane-1-Carboxylate in Calf Thymus DNA.

In the present paper, several computational binding analyses were performed on ethyl 3,3,5,5-tetracyano-2-hydroxy-2-methyl-4,6-diphenylcyclohexane-1-carboxylate which was newly synthesized by three-component condensation of benzaldehyde with ethyl acetoacetate and malononitrile in the presence of trichloroacetic acid, and the structure was finally proved by X-ray analysis. The visualization of molecular interaction was carried out through Hirshfeld surface analysis and ESP. The atomic charges, HOMO, LUMO, and electrostatic potential were also studied to explore the insight of the molecule deeper, and then, natural bonding orbitals (NBO) and non-linear optical properties (NLO) were calculated to reveal the interactions that happen to be between the filled and vacant orbitals.

Magnetic nanocomposites based on phosphorus-containing polymers-structural characterization and thermal analysis.

Fabrication of magnetic nanocomposites containing iron oxide nanoparticles formed in situ within a phosphorus-containing polymer matrix as well as its structural characterization and its thermal degradation is reported here. Comparative structural studies of the parent polymer and nanocomposites were performed using FTIR spectroscopy, x-ray diffraction, and atomic force microscopy. The results confirmed the presence of dispersed iron oxide magnetic nanoparticles in the polymer matrix.

A new approach to ferrocene derived alkenes via copper-catalyzed olefination.

A new approach to ferrocenyl haloalkenes and bis-alkenes was elaborated. The key procedure involves copper catalyzed olefination of N-unsubstituted hydrazones, obtained from ferrocene-containing carbonyl compounds and hydrazine, with polyhaloalkanes. The procedure is simple, cheap and could be applied for the utilization of environmentally harmful polyhalocarbons.

[Pro- and antioxidant effect of electromagnetic fields of extremely high frequency (460 MHz) on brain tissues in experiment].

The article concerns biological effects of non-ionized electromagnetic irradiation which is considered in modern world as a serious ecological factor. Influence of decimetric microwave irradiation (460 MHz) on free radical processes in the rat brain tissues--visual cortex and hypothalamus--were investigated. Oxidative effects of both lipid peroxidation and specific activity of glutathione reductase were determined.

[In vitro study of the modulating effect of antitubercular agents on the rosette formation response in patients with pulmonary tuberculosis].

The wide medical application of new highly active antituberculous agents (ATA) having a definite mechanism of action on immunological homeostasis makes pharmacological regulation of immunological responses real in patients with pulmonary tuberculosis. The purpose of this study was to examine the effect of major ATA on the body's immunological responsiveness in vitro, i.e.