Publications by authors named "A A Leon-Pena"
Article Synopsis
- Lung transplantation for patients with end-stage lung disease from COVID-19 is increasingly common, though there is a lack of comprehensive international studies on the subject.
- In a multicenter analysis involving 11 major lung transplant centers, 46 out of 1606 lung transplants were performed due to COVID-19-related conditions, showing distinct demographic and clinical characteristics compared to other patients.
- The 30-day survival rates for transplant recipients due to COVID-19 were found to be similar to those without COVID-19, suggesting that lung transplantation is a viable option for select patients suffering from COVID-19-related lung damage.
Introduction: Abnormal lung function in people with multiple sclerosis (PwMS) could be considered as the result of muscle weakness or MS-specific structural central nervous system (CNS) abnormalities as a precipitant factor for the worsening of motor impairment or cognitive symptoms.
Methods: This is a cross-sectional observational study in PwMS. Forced spirometry was conducted, and normative metrics of forced vital capacity (FVC), forced expiratory volume in the first second (FEV), and the relation FEV1/FVC were calculated.
Article Synopsis
- The study evaluated long-term outcomes for Hodgkin's lymphoma (HL) treatments in Mexico, focusing on simplified and affordable therapies used over 34 years.
- It involved 88 patients treated with standard chemotherapy regimens (ABVD or MOPP), with outcomes tracked for an average of 128 months.
- Results showed high overall survival rates of 83% for MOPP and 88% for ABVD, suggesting HL may be less aggressive in Mexicans compared to Caucasians, and combined chemotherapy was effective across all clinical stages.
Splitting the Total Dose of Cyclophosphamide in Two Blocks Apart during the Conditioning of Autologous Hematopoietic Stem Cell Transplantation in Multiple Sclerosis Results in Diminished Cardiotoxicity: Experience in 1,000 Patients.
Rev Invest Clin
January 2022
Introduction: We have previously shown that some patients present thrombocytopenia (less than 100 × 10/L platelets) in non-alcoholic fatty liver disease (NAFLD). To further explore the nature of this association, we have now analyzed the association of thrombocytopenia with neutropenia (less than 0.5 × 10/L granulocytes) in NAFLD.
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