[Efficacy of Management for Rational Use of Antibiotics in Surgical Departments at a Multi-Disciplinary Hospital: Results of a 7-year Pharmacoepidemiological Research].

Background: Irrational medicine use including excessive use and abuse of antibiotics remains a crucial problem for the healthcare systems. In this regard, studies examining approaches to improving the clinical use of medicines are highly important.

Aim: to assess the efficacy rate of management for the rational use of antibiotics in surgical departments of a multi-disciplinary hospital.

[The functional features of cell membranes in children with bronchitis and pneumonias].

To develop new differential and diagnostic markers of different types of bronchopulmonary diseases, sodium-lithium countertransport through the red blood cell membrane was studied in 119 children, including 30 patients with bronchitis, 21 with pneumonia, and 68 apparently healthy children (a control group). The majority of patients with pneumonia were found to have the maximum high sodium-lithium countertransport rate as compared with patients with bronchitis, although high sodium-lithium countertransport rates are generally typical of children with bronchopulmonary diseases, as shown by absolute values. These indices may be attributable to the influence of a genetic determinant and environmental factors.

[On the regeneration of transforming reagents in the spray method for the determination of ammonium concentration].

Aerosol method detecting low concentrations of ammonium involves passage of the analysed gas over crystal hydrate of iron nitrate with consequent registration of the aerosol obtained. The method is sensitive and precise due to direct correlation between concentration of the dispersed substance and ammonium level. For precise evaluation and its effectiveness, the crystal hydrate of iron nitrate should be kept over 55-65% nitric acid solution before the analysis.

[Detection of minimal ammonia concentrations using the aerosol method].

The study covered possible detection of ammonium microdoses through passing the analyzed gas over some reagents in order to obtain ammonium aerosol then and register concentration of its dispersed phase. The most effective reagent is crystal hydrate of iron nitrate. Using this reagent makes the technique more precise and handy in comparison with the present ones.