A Method for Automatic Calculation of the Diameter of a Pulsating Blood Vessel on Ultrasound Images in Video Stream Mode.

Three approaches to automatic measurement of the diameter of pulsating blood vessels on ultrasound images in the video stream mode are considered. The use of such approaches for continuous monitoring of vascular wall movements during the cardiac cycle provides for both early diagnosis of cardiovascular diseases and identification of risk factors for these diseases (in particular, vascular atherosclerosis). The operation of the proposed algorithms was studied using sets of ultrasound images of real patients' blood vessels.

YOLOv4-Based CNN Model versus Nested Contours Algorithm in the Suspicious Lesion Detection on the Mammography Image: A Direct Comparison in the Real Clinical Settings.

Background: We directly compared the mammography image processing results obtained with the help of the YOLOv4 convolutional neural network (CNN) model versus those obtained with the help of the NCA-based nested contours algorithm model.

Method: We used 1080 images to train the YOLOv4, plus 100 images with proven breast cancer (BC) and 100 images with proven absence of BC to test both models.

Results: the rates of true-positive, false-positive and false-negative outcomes were 60, 10 and 40, respectively, for YOLOv4, and 93, 63 and 7, respectively, for NCA.

Cystic (including atypical) and solid breast lesion classification using the different features of quantitative ultrasound parametric images.

Purpose: The amount of ultrasound (US) breast examinations continues to grow rapidly because of the wider endorsement of breast cancer screening programs. Cysts are the most commonly diagnosed breast lesions. Atypical breast cysts can be a serious differentiation problem in the US.

[Possibilities of using Mexidol in the complex therapy of mental disorders].

A review of the current literature on the possible use of mexidol (ethylmethylhydroxypyridine succinate) in the treatment of mental (including addictive) disorders is conducted. The possibility of its use to reduce negative psychopathological symptoms, neurocognitive deficit, manifestations of the antipsychotic syndrome (including its extrapyramidal disorders) in antipsychotic treatment of patients with schizophrenia spectrum disorders and insomnia disorders in the complex therapy of borderline mental disorders has been shown. The potential of mexidol in the treatment of addictive pathology, as well as the effects of intoxication caused by alcohol and other psychoactive (including narcotic) substances, deserves special attention.

The possible use of hypoxic preconditioning for the prophylaxis of post-stress depressive episodes.

The protective effects of hypoxic preconditioning on the development of depressive states in rat models were studied. Three episodes of intermittent preconditioning using hypobaric hypoxia (360 mmHg, 2 h) prevented the onset of depressive behavioral reactions, hyperfunction of the hypophyseal-adrenal system, and impairments in its suppression in the dexamethasone test in rats following unavoidable aversive stress in a model of endogenous depression. The anxiolytic and antidepressant actions of hypoxic preconditioning in experiments on rats were no less marked than those of the tetracyclic antidepressant ludiomil.