Publications by authors named "A A Kocaeli"
Concurrent presence of diabetes affects the GLUT3 programming of glucose metabolism in glioblastoma.
Eur Rev Med Pharmacol Sci
September 2023
Objective: Diabetes mellitus (DM)-mediated impaired glucose metabolism increase in the glioblastoma (GB) risk by inducing hyperglycemia and hyperinsulinemia. An integral membrane transport protein, glucose transporter 3 (GLUT3) facilitates glucose transport into GB tumor cells. We aimed to explore the regulation of GLUT3 in GB tumors of patients who were concurrently diagnosed with DM.
View Article and Find Full Text PDFAim: To describe the role of metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) in glioblastoma (GB) progression in patients concurrently diagnosed with diabetes mellitus (DM).
Material And Methods: Formalin-fixed paraffin-embedded (FFPE) tumor samples of 47 patients diagnosed with GB only and 13 patients diagnosed with GB and DM (GB-DM) were enrolled in this study. Data for p53 and Ki67 immunohistochemical staining of the tumors and blood HbA1c levels of patients with DM were retrospectively collected.
Article Synopsis
- A study evaluated the effects of bariatric surgery over one year, analyzing postoperative complications, mortality, and weight loss in 101 patients who underwent either laparoscopic sleeve gastrectomy (LSG) or Roux-en-Y gastric bypass (RNYGB).
- The patients had an average age of about 38 years and a high body mass index (BMI) of around 49 kg/m²; LSG was the more common procedure, and the overall complication rate was 7.92%.
- Significant improvements were noted in comorbidities like diabetes, hypertension, and obstructive sleep apnea, with LSG and RNYGB being particularly effective for patients with a BMI over 50 kg/m²;
Background: Persistent hypercalcemia and hyperparathyroidism after successful kidney transplantation can be detrimental in some recipients and should be ameliorated.
Objective: To point out the concerns regarding resistance to cinacalcet in kidney transplant recipients with persistent hypercalcemia.
Methods: 14 renal transplant recipients who received cinacalcet treatment because of persistent hypercalcemia were included in the study.