[Hemodynamics in puerparas during subarachnoidal anesthesia with lidocaine].

Hemodynamic changes in response to subarachnoidal injection of 1.2-1.4 mg/kg of lidocaine at various concentrations were comparatively evaluated in 106 pregnant women aged 21 to 36 years (with 53 patients in each group).

[Brain injuries in relation to morphological structure of dura mater spinalis in pregnant women].

Morphological and histochemical investigations on dura mater spinalis of the lumbar site in 5 women of reproductive age dead from accidents and 5 women dead during deliveries due to hemorrhage were carried out. It was found that one of the etiological factors of head-aches after subarachnoid anesthesia was functional reduction of mechanic and supporting function of dura mater spinalis along with elasticity loss of fibrous tissue, edema and friability. The stable non-healing postpuncture defect of dura mater spinalis resulted in liquorrhea with subsequent development of the "liquorrhea hypotension" syndrome.

[Lymphotropic antibiotic therapy of obstetrical suppurative-septic diseases].

The pharmacokinetics and efficacy of gentamicin after its direct and indirect endolymphatic administration were comparatively studied. It was shown that the time course of the blood pharmacokinetics of the antibiotic was almost the same as under the both conditions. Therefore, in many cases the less complicated and more available indirect endolymphatic therapy may replace the direct labor-consuming and traumatic endolymphatic administration of drugs.