[Modern approaches to dental implants placement in deficient alveolar bone].

The paper presents statistical data on implant placement procedures in Central Research Institute of Dentistry and Maxillofacial Surgery (Moscow, Russia) in 2010-2015. In 64% of cases inadequate bone volume was attributed to alveolar bone atrophy. Bone deficiency was equally often in upper and lower jaws (in 49.

[Endoplasmic reticulum stress, its sensor and signalling systems and the role in regulation of gene expression at malignant tumor growth and hypoxia].

Hypoxia is one of the inductors of the expression of a large group of genes, which control glycolysis and proliferation processes in low oxygen conditions or as a result of low oxygen consumption. Moreover, hypoxia is one of the factors which induce the endoplasmic reticulum stress which, like hypoxia, is an obligatory component of malignant tumor growth and is connected with cytoplasm and nuclei through three sensor and signalling systems: PERK, ATF6 (Ta) ERN1. The suppression of ERNI, the main sensing and signalling enzyme of endoplasmic reticulum stress, leads to a decrease of tumor growth and changes the character of hypoxic regulation of many genes responsible for the control of proliferation and glycolysis.

[Microcirculation status in supporting tissues in cases of prosthetic treatment of mandible in patients with full secondary adentia with the use of implants].

By the method of laser Doppler fluometry microcirculation in gingival tissues was studied in the region of bearing implants in cases of making prosthetics for patients with full secondary adentia. It was established that after functional loading of the bearing implants in microcirculatory bed of gingival tissues hyperemia was developed that was cut short in 3 months that testified to normalization of tissue blood flow.

[Comparative assessment of adaptation processes in abutment tissues after prosthetic treatment with the use of dental implants according to microcirculatory indices].

Gingival tissue blood circulation restoration after single implant implantation set in 4 and in 6 months after 2-3 implants introduction. In cases of abutment implant functional loading when treating partial dentition defect by single crowns and constructions with 2-3 abutment implants hyperemia was developed in gingival tissue microcirculatory bed that was later cut short in 1 and 6 months correspondingly.