Neurohistological, newchistochemical and ultrastructural analysis in pia mater and brain cortex auditory zone in tumors of hypothalamo-hypophyseal localization (12 patients) and dozaged experimental influence on hypothalamus (60 rabbits with 30 control and 30 experimental ones) allowed to establish and follow up morphofunctional and pathological changes. The former appeared previously in adrenergic nerve structures of pia mater and cortical vascular bed and neuroglia, the latter--in cortical neurons. The results obtained may be used in otoneurology and neurosurgery in elucidation certain syndromes genesis, acoustic ones included in patients with tumors of mentioned localisation, directly influencing hypothalamic area.
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