Publications by authors named "A A Gonzalez-Ibarra"
Article Synopsis
- Ribosomal function is enhanced by trans-acting factors and ribosomal elements, with phosphorylation playing a key regulatory role.
- The ribosomal P-stalk, which consists of five phosphorylated C-terminal domains, activates translational GTPases and connects to the Gcn2 kinase within the integrated stress response (ISR) pathway.
- Unlike most ribosomal proteins, P-stalk proteins remain in a constantly phosphorylated state, promoting optimal translation efficiency and allowing flexible interaction with various protein partners.
Coal has been a valuable natural resource for Mexico not just for its relative abundance but for its critical role in the development of the steel and energy industries. It has been also important in the socioeconomic context of the northeast of the country. However, since years ago, coal mining is facing a transition due to the emergence of new energy sources and the public concern about global warming.
View Article and Find Full Text PDFBiochar is a carbonaceous and porous material with limited adsorption capacity, which increases by modifying its surface. Many of the biochars modified with magnetic nanoparticles reported previously were obtained in two steps: first, the biomass was pyrolyzed, and then the modification was performed. In this research, a biochar with FeO particles was obtained during the pyrolysis process.
View Article and Find Full Text PDFIdentification of a novel alternatively spliced isoform of the ribosomal uL10 protein.
Biochim Biophys Acta Gene Regul Mech
March 2023
Article Synopsis
- Alternative splicing increases the complexity and adaptability of genetic information in higher eukaryotes, leading to various protein isoforms, although many remain functionally uncharacterized.
- The study identifies and characterizes a new isoform of the ribosomal uL10 protein, called uL10β, which plays a critical role in the structure and function of the ribosome.
- Findings show that uL10β is stably expressed in mammalian cells, primarily located in the nucleus, and potentially has a unique function during endoplasmic reticulum stress by relocalizing to mitochondria and associating with certain ribosomal particles.
Antinociceptive effects of Laelia anceps Lindl. and Cyrtopodium macrobulbon (Lex.) G.A. Romero & Carnevali, and comparative evaluation of their metabolomic profiles.
J Ethnopharmacol
June 2022
Ethnopharmacological Relevance: Laelia anceps and Cyrtopodium macrobulbon are two orchids used in Mexican traditional medicine for treating pain.
Aim Of The Study: The individual antinociceptive activity of ethanol extracts from the roots of Laelia anceps (LAE) and Cyrtopodium macrobulbon (CME) was evaluated, and their metabolomic profiles were comparatively evaluated. The antinociceptive activity of CME and naproxen combination (1:1) was also addressed.