Pulmonary lymphangioleiomyomatosis.

This paper reports a case of a 50 yr old premenopausal woman with pulmonary lymphangioleiomyomatosis. This asymptomatic woman was found to have 'pulmonary nodules' on routine chest x-ray simulating metastatic lesions. The final diagnosis was possible after pathological examination of the lung biopsy specimens.

Computerised tomography does not predict N2 disease in patients with lung cancer.

Background: Mediastinal node involvement in primary lung cancer determines the staging and prognosis of the patient, and as these nodes can be seen on the computerised tomography (CT) scan of the chest it is a temptation to diagnose malignant involvement if the nodes appear enlarged. However, initial experience with mediastinal node mapping at lung resection demonstrated this extrapolation to be unreliable and misinterpretation of enlarged nodes on CT may lead to misdiagnosis and prejudice the patient's management.

Aim: To demonstrate that the sensitivity, specificity, and accuracy of the CT to detect malignant mediastinal nodes is too low to use size of node on CT as representative of malignant involvement.

Amiodarone pulmonary toxicity--three unusual manifestations.

Amiodarone is very useful treatment for refractory arrhythmias. However, it has a wide profile of adverse effects involving a number of organ systems. Pulmonary toxicity is the most serious of these side effects and often limits its clinical use.

Primary leiomyosarcoma of the heart: a rare cause of obstruction of the left ventricular outflow tract.

Primary cardiac tumours are rare and frequently only diagnosed post-mortem. Recent improvements in non-invasive imaging techniques have led to an increasing number being diagnosed in life, allowing surgical resection. We report a primary leiomyosarcoma presenting with obstruction of the left ventricular outflow tract.