Publications by authors named "A A Ferrante"

Low temperature is the main strategy to preserve fruit quality post-harvest, in the supply chain. Low temperatures reduce the respiration, ethylene emission, and enzymatic activities associated with senescence. Unfortunately, peaches are sensitive to low temperatures if exposed for long periods, resulting in physiological disorders that can compromise commercial quality.

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Niemann Pick type C1 (NPC1) is a rare, fatal disorder characterized by endosomal lipid accumulation that leads to damage of both peripheral organs and central nervous system (cerebellum and hippocampus are especially affected). Currently, miglustat is the only approved drug for NPC1, thus the identification of new treatments is mandatory. We have previously demonstrated that the drug dipyridamole (DIP), an enhancer of adenosine signaling, can reduce the pathological phenotype in patient-derived fibroblasts.

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  • The study investigates the effects of a plant-derived biostimulant from borage flowers on two types of lettuce, assessing its impact on crop yield, quality, and stress tolerance.
  • The biostimulant was applied as a foliar spray over three weeks, with a focus on measuring various growth parameters and conducting both non-destructive and destructive analyses.
  • Results showed that while the biostimulant negatively impacted head weight in the red lettuce cultivar, it improved nitrogen nutrition in the green cultivar and influenced factors like chlorophyll efficiency and anthocyanin levels differently between the two lettuce types.
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  • Reduced levels of Protein Kinase C (PKC)ζ in cord blood T cells are linked to the development of allergies in children and a tendency to favor an immature T-helper (Th)2 cytokine response.* -
  • Cord blood monocytes and neutrophils also exhibit low levels of various PKC isozymes compared to adult blood, indicating a broader deficiency in these immune cells.* -
  • While PKCζ levels in cord blood T cells correlate with those in monocytes, this does not influence the differentiation of the T cells towards Th1 or Th2 cytokine profiles, unlike in T cells.*
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Background: This study examines the effects of levosimendan in patients refractory to dobutamine weaning.

Methods: This retrospective study included patients with cardiogenic shock refractory to dobutamine weaning failure admitted between 2010 and 2022. Patients treated with another type of dobutamine alone were compared with those treated with levosimendan in combination with dobutamine.

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