Publications by authors named "A A Economides"
This study investigates the quasi-static and viscoelastic properties of additively manufactured (AM) PETG reinforced with short carbon fibres. Samples were manufactured using different parameters in terms of the infill pattern, porosity, and annealing condition. Tensile and compressive tests were conducted to determine quasi-static properties such as Young's modulus and toughness, and dynamic mechanical analysis was used under a frequency sweep of 1-100 Hz to describe the viscoelastic behaviour of the composites.
View Article and Find Full Text PDFRecent studies have revealed a role for zinc in insulin secretion and glucose homeostasis. Randomized placebo-controlled zinc supplementation trials have demonstrated improved glycemic traits in patients with type II diabetes (T2D). Moreover, rare loss-of-function variants in the zinc efflux transporter reduce T2D risk.
View Article and Find Full Text PDFBackground: Adiposity may be associated with thyroid nodularity. However, its impact on the number of nodules and the risk of malignancy is unclear.
Aim: To evaluate the impact of adiposity on thyroid nodules using body mass index (BMI), ultrasonographic (US) data and cytological data.
Article Synopsis
- Fibrodysplasia ossificans progressiva (FOP) is a rare condition where bones form in soft tissue, referred to as heterotopic ossification (HO), and this study examined imaging methods to identify and measure new HO lesions.
- The research analyzed data from a phase 2 clinical trial comparing the effectiveness of garetosmab (a therapy) with a placebo in adults with FOP, utilizing both PET/CT and CT scans to detect lesions over 28 weeks.
- Results showed that both PET/CT and CT-only methods detected a similar number and volume of new lesions, indicating that CT-only imaging is an effective alternative for monitoring HO changes in FOP patients.
Article Synopsis
- The genetic factors contributing to stroke risk in South Asians remain largely unstudied, with a recent study examining 75,000 Pakistanis using exome-wide sequencing.
- A specific genetic variant, NOTCH3 p.Arg1231Cys, was found to be more common in South Asians (0.58%) compared to Western Europeans (0.019%) and was significantly linked to hemorrhagic and overall stroke risk.
- This variant accounts for about 2.0% of hemorrhagic strokes and 1.1% of all strokes in South Asians, emphasizing the importance of including diverse populations in genetic research for better understanding and treatment of stroke.