The efficacy of curcumin-piperine supplementation in patients with nonproliferative diabetic retinopathy: An optical coherence tomography angiography-based randomized controlled trial.

Background: Diabetic retinopathy (DR) is one of the complications of diabetes. This study was conducted to investigate the effect of curcumin-piperine on laboratory factors and macular vascular in DR.

Materials And Methods: The present study was a randomized, placebo-controlled, double-blind, parallel-arm clinical trial that was conducted on 60 patients with DR aged 30-65 years.

Comparing the effectiveness of curcumin and papain in wound dresses based on chitosan nanoparticle.

In this study, chitosan/curcumin (CS/Cur) and chitosan/papain (CS/Pa) nanoparticles were prepared and then characterized by Fourier transform infrared (FTIR), X-ray diffraction (XRD), and differential light scattering (DLS). Subsequently, release rate, porosity, swelling, degradability, anti-inflammatory, antioxidant, antibacterial, and cell viability tests were conducted to investigate and compare the healing potential of the nanoparticles for various types of wounds. The results of FTIR, XRD, and DLS indicated that the nanoparticles were manufactured correctly with a hydrodynamic diameter of 429 nm (CS/Cur) and 460 nm (CS/Pa), and zeta potential of 4.

Early Detection of Diabetic Nephropathy Based on Urinary and Serum Biomarkers: An Updated Systematic Review.

Diabetic nephropathy (DN) is a leading cause of chronic kidney disease (CKD) and end-stage renal disease worldwide, particularly among individuals with type 2 diabetes mellitus (T2DM). Early detection and intervention are crucial in slowing the progression of DN and improving patient outcomes. Traditional diagnostic methods, such as the measurement of albuminuria and serum creatinine, often fail to detect early renal damage because structural kidney damage may occur before albumin excretion.

Agenda-setting for iron deficiency anaemia prevention and control policies in Iran by multiple streams framework.

Background: According to the WHO report and evaluations, Iran has a moderate prevalence of iron deficiency anaemia (IDA). The present study evaluates Iran's IDA prevention and control policies by analysing the agenda-setting policy using the multiple streams framework (MSF).

Methods: The present study used Kingdon's MSF model to analyse policies related to IDA in Iran qualitatively.

Asymptomatic migration of ureteral stent to superior vena cava after ultrasound-guided percutaneous nephrolithotomy: An extremely rare case and review of the literature.

Ureteral stent migration should be considered a rare complication of urologic procedures. We report a 69-year-old woman diagnosed with ureteral stent migration two weeks after undergoing percutaneous nephrolithotomy while she was symptom-free. The stent passed through the heart and extended to the superior vena cava and right brachiocephalic vein.