[Neurofeedback in the treatment of cognitive impairment in patients with early cerebral small vessel disease].

Objective: To compare the effectiveness of neurofeedback (NFB) at infra-low and alpha frequencies in the treatment of cognitive impairment in patients with early cerebral small vessel disease (cSVD).

Material And Methods: The study included 71 patients (average age 52.8±6.

[Disruption of corpus callosum microstructural integrity by diffusion MRI as a predictor of progression of cerebral microangiopathy].

Objective: To assess the microstructural integrity of the corpus callosum in patients with cerebral small vessel disease (cSVD) using signal and biophysical diffusion MRI models and to identify the most sensitive markers of disease progression.

Material And Methods: Diffusion MRI (3 Tesla) was performed in 166 patients (51.8% women; mean age 60.

[Nitric oxide availability in cerebral microangiopathy].

Objective: To develop a test of individual nitric oxide (NO) availability based on changes in erythrocyte rheological properties after incubation with a NO donor and to evaluate the role of these disorders in brain damage and development of cognitive impairment (CI) in cerebral small vessel disease (cSVD).

Material And Methods: In 73 cSVD patients (48 (65.8%) women, mean age 60.