Age-related features of the content of substrates of energy metabolism and body mass index in women residing in the Subarctic and Arctic regions of Russia.

Objectives: Age is associated with a number of health risks linked to obesity caused by an imbalance in the main energy substrates-fatty acids (FA) and glucose (Glu). Therefore, the objective of this study was to identify age-related features of the metabolism of fatty acids and Glu, their correlations and the relation with the body mass index (BMI) in women of the local Caucasoid population from two northern regions of Russia with different nature, climate, and geography.

Methods: We examined women aged 21-60 years born and permanently residing in the Subarctic region (SR) and the Arctic region (AR).

[Correlation of parameters of carbohydrate metabolism and saturated fatty acids in blood serum in elderly people.].

The study involved 106 elderly people of the Arctic aged 61-74 years, 42 of them were residents of the Subarctic region (SR) and 64 residents of the Arctic region (AR). Using gas-liquid chromatography there was determined the serum content of saturated fatty acids (SFA): short-chain (SCFA), medium-chain (MCFA) and long-chain (LCFA); and the levels of carbohydrate metabolism parameters were determined by spectrophotometric methods. Correlation analysis showed that elderly people of SR had no significant interrelationships between the contents of SCFA, MCFA and LCFA, since all the correlation dependences were weak (r=0,2-0,29, p=0,08-0,786), against AR with a lower occurrence of high values of glucose (Glu), lactate (Lac) and low pyruvate (Pyr).