Inhibitory control dysfunction in parkinsonian impulse control disorders.

Impulse control disorders (ICDs) in Parkinson's disease have been associated with dysfunctions in the control of value- or reward-based responding (choice impulsivity) and abnormalities in mesocorticolimbic circuits. The hypothesis that dysfunctions in the control of response inhibition (action impulsivity) also play a role in Parkinson's disease ICDs has recently been raised, but the underlying neural mechanisms have not been probed directly. We used high-resolution EEG recordings from 41 patients with Parkinson's disease with and without ICDs to track the spectral and dynamical signatures of different mechanisms involved in inhibitory control in a simple visuomotor task involving no selection between competing responses and no reward to avoid potential confounds with reward-based decision.

[Geriatric properties of a bioantioxidant complex ginseng on model of the accelerated radioactive aging].

The work starts studying the geriatric properties of the bioantioxidant complex "Neovitin" received from a biomass of ginseng, on model of accelerated radioactive aging. The preparation was applied before radioactive irradiation to study its preventive effect, and after irradiation to study the therapeutic effect. Efficiency of the complex was estimated by the survival rate of animals after irradiation in the experimental model.

[Elastase and acid phosphatase activity in bronchoalveolar lavage fluid during chronic bronchitis].

The dynamics of acid phosphatase and granulocytic elastase activities in bronchoalveolar washings of 40 patients with chronic catarrhal bronchitis was studied. In case of effective cure, the activities of these enzymes were increased shortly on the 10-13 days from beginning of the cure. In order to study the nature of this enzymes, the additional researches were conducted.