Publications by authors named "A A B Murashima"
Aim: Uncontrolled chronic inflammatory diseases (CIDs) before, during, and after pregnancy, as well as some CID medications, can increase the risk of impaired fertility in addition to adverse maternal/pregnancy outcomes in women of childbearing age. We report pregnancy outcomes from prospectively reported pregnancies in Japanese women treated with certolizumab pegol (CZP).
Methods: Data from July 2001 to November 2020 on CZP-exposed pregnancies from the CZP Pharmacovigilance safety database were reviewed.
We evaluated the teratogenic risk associated with exposure to cefditoren pivoxil during the first trimester of pregnancy using the integrated databases of the Toranomon Hospital and the National Center for Child Health and Development. Among 13 599 registered individuals, the analysis included 285 subjects who had taken cefditoren pivoxil during the first trimester of pregnancy. The rates of stillbirth, miscarriage, and elective terminations were 0.
View Article and Find Full Text PDFEffects of famotidine use during pregnancy: an observational cohort study.
J Pharm Health Care Sci
November 2024
Background: Famotidine, a histamine2-receptor antagonist (H2Ras), is widely used to treat and prevent gastrointestinal symptoms during pregnancy. Although several studies have reported the use of H2Ras during pregnancy, limited data on famotidine were included in these reports. Therefore, we analyzed pregnancy outcome data to evaluate the effects of famotidine use during pregnancy on the fetus.
View Article and Find Full Text PDFArticle Synopsis
- - The study investigates the challenges that nurses encounter when caring for older patients with rheumatoid arthritis (RA) in Japan, using responses from certified nurses to identify key issues.
- - A total of 182 specific challenges were categorized into seven components, focusing on patient-related issues such as comprehension, support, comorbidities, and financial constraints, as well as challenges faced by nurses themselves.
- - The findings highlight the need for better patient understanding, improved nurse training, and enhanced support systems, emphasizing the importance of teamwork and family involvement in patient care.
Objective: This systematic scoping review assess the effect of cyclophosphamide (CY) administration during childhood on ovarian function in patients with juvenile-onset connective tissue diseases.
Methods: A MEDLINE database search was conducted using terms related to CY, juvenile-onset connective tissue diseases, and ovarian function. Studies were included if they met specific criteria.