Publications by authors named "A A Ashour"
Background: Naming is an important part of human communication. The precision of medical terms greatly influences the patients and their caregivers. "Alsara'الصرع " is the Arabic term defining epilepsy.
View Article and Find Full Text PDFThe antioxidant/antiapoptotic features of dapagliflozin (DPG) have mediated its beneficial actions against several experimental models. However, no studies have been conducted to determine whether DPG mitigates the renal injury triggered by cadmium (Cd). Herein, DPG was studied for its potential to attenuate kidney damage in Cd-intoxicated rats, as well as to unravel the mechanisms involving oxidative events, autophagy, and apoptosis.
View Article and Find Full Text PDFIntroduction: First metatarsophalangeal (MTP) joint fusion is a widely accepted surgical intervention for treating severe arthritis, deformities, and instability of the first MTP joint. This paper provides a review of a single surgeon's experience with continuous compression implants (CCI), which offer a notable advantage by providing uniform compression across a larger surface area of the fusion site compared to plate and screw constructs. This design potentially reduces soft tissue irritation and, consequently, the need for subsequent implant removal.
View Article and Find Full Text PDFA simple and highly effective Schiff-base fluorescent chemosensor (S1) was synthesized and characterized by HNMR and fluorescence spectroscopy. The synthesized chemosensor was applied for the selective and sensitive detection of Hg ions. The chemosensor exhibited a strong 'turn-on' fluorescence response in a CHOH/HO (1:9, v/v) solution due to complex formation (S1-Hg) which block photo induce electron transfer (PET).
View Article and Find Full Text PDFArticle Synopsis
- The increasing issue of multidrug resistance (MDR) in pathogenic bacteria like Staphylococcus aureus has prompted the search for new treatment methods, including FDA-drug repurposing.
- Ambroxol was tested against clinical MDR S. aureus isolates and showed effective antibacterial activity, with concentrations needed to inhibit growth between 0.75 to 1.5 mg/mL, and also disrupted biofilm formation in about 42% of the isolates.
- In vivo studies demonstrated ambroxol's ability to enhance skin tissue healing in S. aureus infected burn injuries by reducing bacterial presence and inflammation, with further investigations suggesting its action may involve binding to several targets in the bacterium.