Publications by authors named "A A Artyukhin"
Fatty acid desaturation is central to metazoan lipid metabolism and provides building blocks of membrane lipids and precursors of diverse signaling molecules. Nutritional conditions and associated microbiota regulate desaturase expression, but the underlying mechanisms have remained unclear. Here, we show that endogenous and microbiota-dependent small molecule signals promote lipid desaturation via the nuclear receptor NHR-49/PPARα in C.
View Article and Find Full Text PDFFatty acid desaturation is central to metazoan lipid metabolism and provides building blocks of membrane lipids and precursors of diverse signaling molecules. Nutritional conditions and associated microbiota regulate desaturase expression, but the underlying mechanisms have remained unclear. Here, we show that endogenous and microbiota-dependent small molecule signals promote lipid desaturation via the nuclear receptor NHR-49/PPARα in .
View Article and Find Full Text PDFThe larches of Kuzhanovo ( Ledeb.) are protected trees with a round crown growing in the Southern Urals. In 2020 vandals sawed the sapwood of these trees, which exposed the problem of insufficient conservation measures.
View Article and Find Full Text PDFArticle Synopsis
- Recent studies show significant differences in the metabolites between male and hermaphrodite C. elegans, highlighting the role of sex in organismal biology.
- Using untargeted comparative metabolomics, researchers identified many small molecules that are either exclusive to one sex or produced in much larger quantities, including new metabolites from various metabolic pathways.
- One male-specific metabolite, a dipeptide, was found to increase food consumption, shorten lifespan, and speed up larval development in hermaphrodites, suggesting a genetic link between sex and metabolic functions.