[Comparative characteristics of depressive tendencies in patients with tuberculosis and chronic obstructive pulmonary disease].

Chronic obstructive pulmonary disease (COPD) and tuberculosis are socially significant diseases that can develop at any age, and require long-term, sometimes lifelong, therapy. Diseases will inevitably cause a deficiency of oxygen in the body that can cause disorders of the nervous system, from the mood changes to reduce intelligence, especially in the elderly. According to the results of the study the majority of patients with COPD and a third of patients with tuberculosis, there are significant problems of the emotional plane, especially in older and elderly expressed in the presence of depressive tendencies (from subdepressive states to real depression), and almost half of the patients in need of specially organized psychological or medical assistance.

[Mechanism of the protective action of acetylcholine and serotonin against their cytotoxic antagonists].

By means of biological testing on supersensitive embryos of the sea-urchin Arbacia lixula, it has been shown that the eggs and embryos of the sea-urchin Paracentrotus lividus incubated in solutions of cytotoxic neuropharmacological drugs (cholino- and serotoninolytics), accumulate the latter. During the first (rapid) stage of binding, a level is reached which is 2-6 times higher than the external concentration; during the second stage of binding, this level gradually increases up to the values which are 8-12 times higher than the external concentration. The protecting action of exogenous acetylcholine and serotonin against the drugs studied does not inhibit their accumulation in embryonic cells.