The spiritual possession phenomenon (SPP), is a complex transnosological, transcultural syndrome, which is based on the patients' perception that some spiritual entity (spirit, demon, jinn, shaitan, «ikotka», dybbuk, Buddha, etc.) is influencing or possessing them. Modern classifications of diseases, aimed at expanding our ideas about the distinction between the norm and pathology of mental disorders, do not contribute to a clear psychopathological differentiation of SPP, the determination of its nosological affiliation and the choice of appropriate therapeutic tactics for these conditions.
View Article and Find Full Text PDFTamarind seed polysaccharide (TSP) is a neutral water-soluble galactoxyloglucan isolated from the seed kernel of with average molecular weight (Mw) 600-800 kDa. The high viscosity of TSP slows solubilisation, and the absence of charged substituent hinders the formation of electrostatic interactions with biomolecules. TSP was sulphated in a one-step process using dimethylformamide as a solvent, and sulphur trioxide-pyridine complex as a sulphating reagent.
View Article and Find Full Text PDFZh Vopr Neirokhir Im N N Burdenko
December 2024
Unlabelled: The development of new drugs in nuclear medicine for diagnosis or treatment (chemotherapy) of brain tumors, in particular gliomas, is inextricably linked with the use of tumor models in animals (usually rats).
Objective: To compare the widely used glioma cell model C6 and the new experimental tissue model of glioblastoma 101.8.
One of the urgent tasks of modern medicine is to detect microcirculation disorder during surgery to avoid possible consequences like tissue hypoxia, ischemia, and necrosis. To address this issue, in this article, we propose a compact probe with sapphire tip and optical sensing based on the principle of spatially resolved diffuse reflectance analysis. It allows for intraoperative measurement of tissue effective attenuation coefficient and its alteration during the changes of tissue condition, caused by microcirculation disorder.
View Article and Find Full Text PDFCurrent therapy protocols fail to cure high-grade gliomas and prevent recurrence. Therefore, novel approaches need to be developed. A re-programing of glioma cell fate is an alternative attractive way to stop tumor growth.
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