Renal Juxtaglomerular Cell Tumors Exhibit Distinct Genomic and Epigenomic Features and Lack Recurrent Gene Fusions: Comprehensive Molecular Analysis of a Multi-institutional Series.

Juxtaglomerular cell tumor (JxGCT) is a rare type of renal neoplasm demonstrating morphologic overlap with some mesenchymal tumors such as glomus tumor (GT) and solitary fibrous tumor (SFT). Its oncogenic drivers remain elusive, and only a few cases have been analyzed with modern molecular techniques. In prior studies, loss of chromosomes 9 and 11 appeared to be recurrent.

Cluster of Legionellosis Cases Associated with Manufacturing Process, South Carolina, USA, 2022.

Evolving technology and the development of new devices that can aerosolize water present a risk for new sources of Legionella bacteria growth and spread within industrial settings. We investigated a cluster of legionellosis among employees of a manufacturing facility in South Carolina, USA, and found 2 unique equipment sources of Legionella bacteria. The cluster of cases took place during August-November 2022; a total of 34 cases of legionellosis, including 15 hospitalizations and 2 deaths, were reported.

Differential expression of metabolic enzymes in testicular germ cell tumors: The impact of glycolytic metabolism in embryonal carcinoma histotype.

Background: Testicular germ cell tumors are the most common solid malignancies in young men, with increasing incidence worldwide. Broadly classified into seminomas and non-seminomas, they exhibit distinct biological behaviors and responses to treatment. Although metabolic reprogramming is an acknowledged cancer hallmark, metabolic pathways in testicular germ cell tumors remain poorly understood.

What Happens When Undergraduate Biology Students Meet with Professional Scientists to Discuss Research? An Exploratory Investigation into Scientific Discourse, Motivation, and Sense of Belonging.

Engagement in scientific discourse is an essential part of becoming a scientist. In this exploratory study, we aim to examine the scientific discourse (and resulting benefits) between undergraduate biology students and professional scientists. We developed a novel method for engaging in scientific discourse, grounded in the theory of legitimate peripheral participation, where undergraduate biology students participate in communities of practice within their own departments.

Results of the proficiency test for the Ka CMC of the SSDL-ININ Mexico, for diagnostic radiology IEC 61267:2005 and radiation protection ISO 4037:2019 X-ray beam qualities.

The present work describes the results for the bilateral comparison between the Secondary Standards Dosimetry Laboratories of the Instituto Nacional de Investigaciones Nucleares (SSDL-ININ), Mexico, and the pilot laboratory, the Centro de Protección e Higiene de las Radiaciones (SSDL-CPHR), Cuba, for the realization of the air kerma (${\boldsymbol{K}}_{\boldsymbol{a}}$) quantity to: (i) diagnostic X-ray (DXR) IEC 61267:2005 beam qualities: RQR 5 RQR 9, RQT 8, and RQT 9 and (ii) radiation protection (RP) ISO 4037:2019 X-ray beam qualities: N60, N100, and W60, as well S-Cs for gamma radiation. The matched and characterized reference fields are realized at SSDL-ININ with a Toshiba E7252FX X-ray tube. In all cases, the ${\boldsymbol{K}}_{\boldsymbol{a}}$ measurements are traceable to PTB, except for S-Cs, traceable to ININ.