Publications by authors named "A A Abiodun"
The rise of antibiotic resistance, biofilm formation, and dormant bacterial populations poses serious global health threats. Synthetic antimicrobial peptide (AMP) mimics offer promising alternatives, though the impact of secondary structures in polymeric AMP mimics on antimicrobial efficacy is underexplored. This study investigates chirality-controlled α-peptide polymers (D-PP and DL-PP), synthesized via ring-opening polymerization of allylglycine -carboxy anhydrides and post-polymerization modification through thiol-ene click chemistry.
View Article and Find Full Text PDFIntroduction/background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. The AF Atrial Fibrillation Registry, which commenced in June 2023, was designed to provide clinical epidemiological data on patients with AF in the country.
Objective(s): The objective is to describe the rationale, design, and early findings from the registry.
Article Synopsis
- Chronic heart failure (CHF) presents distinct gender-specific factors that impact patient care, yet women are underrepresented in related studies, highlighting a need for more focused research.
- This study examines 1,290 CHF patients to analyze gender differences in causes, comorbidities, treatment, and one-year mortality rates.
- Findings reveal that men, who made up 55.8% of the study group, generally had worse health outcomes, prevalent comorbidities, and higher mortality rates compared to women, suggesting significant gender disparities in CHF profiles.
Background: Menstrual irregularities significantly distress women living with HIV (WLHIV), impacting their reproductive health and quality of life. Although the underlying mechanism remains inconclusive, studies have outlined possible contributory factors. This narrative review explores the burden of menstrual irregularities and associated hormonal dysregulation among women living with HIV in Nigeria.
View Article and Find Full Text PDFUndertaking a period of research in cardiology is considered a vital part of training. This has many advantages including enhancing skills that better equip the clinician for patient care. However, in modern cardiology training, the feasibility and necessity of undertaking a period of formal research during training should be considered on an individual basis.
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