c-FLIP/Ku70 complex; A potential molecular target for apoptosis induction in hepatocellular carcinoma.

Hepatocellular carcinoma (HCC) is one of the most lethal malignancies worldwide and the most common form of liver cancer. Despite global efforts toward early diagnosis and effective treatments, HCC is often diagnosed at advanced stages, where conventional therapies frequently lead to resistance and/or high recurrence rates. Therefore, novel biomarkers and promising medications are urgently required.

Perioperative management of a patient with severe aortic stenosis and chronic obstructive pulmonary disease undergoing abdominal aortic aneurysm repair: A case report.

Introduction And Importance: Severe aortic stenosis (AS) and chronic obstructive pulmonary disease (COPD) significantly increase perioperative morbidity and mortality. This case report discusses the challenges of managing a 75-year-old male patient with severe AS and advanced COPD undergoing elective abdominal aortic aneurysm (AAA) repair.

Case Presentation: The patient presented with a 6.

A Promising Druggable Target for Translational Therapy of Ovarian Cancer: A Molecular Profiling of Therapeutic Innovations, Extracellular Vesicle Acquired Resistance, and Signaling Pathways.

Ovarian cancer (OC) ranks as the fifth leading cause of cancer-related deaths in the United States, posing a significant threat to female health. Late-stage diagnoses, driven by elusive symptoms often masquerading as gastrointestinal issues, contribute to a concerning 70% of cases being identified in advanced stages. While early-stage OC brags a 90% cure rate, progression involving pelvic organs or extending beyond the peritoneal cavity drastically diminishes it.

Digital cervicography using mobile phones with real-time consultation (DCRC) to improve performance of Visual Inspection with Acetic Acid (VIA) in cervical cancer screening of HIV-infected women. A cross-sectional study.

Introduction: Visual Inspection with Acetic Acid (VIA) has been adopted for cervical cancer screening in Kenya and other Low-Middle Income Countries despite providing suboptimal results among HIV-infected women. It is mostly performed by nurses in health centers. Innovative ways of improving the performance of VIA in HIV-infected women are desired.

Antifouling Copper Surfaces Interfere with Wet Chemical Nitrate Sensors: Characterization and Mechanistic Investigation.

Wet chemical sensors autonomously sample and analyze water using chemical assays. Their internal fluidics are not susceptible to biofouling (the undesirable accumulation of microorganisms, algae, and animals in natural waters) due to the harsh chemical environment and dark conditions; however, the sample intake and filter are potentially susceptible. This paper describes the use of copper intake filters, incorporated to prevent fouling, on two different wet chemical nitrate sensors that each use different variants of the Griess assay (in particular, different nitrate reduction steps) to quantify nitrate concentrations.