Stability study of a nisin/natamycin blend by LC-MS.

Nisin and natamycin are natural preservatives used in a broad range of food products. In the present study, the stability of an aqueous nisin/natamycin blend (pH 4.0) for the beverage market was tested at room temperature (22 °C) under dark conditions by means of liquid chromatography.

Selective and sensitive determination of lactose in low-lactose dairy products with HPAEC-PAD.

The demand for low lactose dairy products is increasing and more different lactose free food is commercially available. The level of lactose in these products decreased during the last years and nowadays a concentration of <0.01% is generally accepted as "lactose free".

Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum.

The cholesterol-lowering blockbuster drug pravastatin can be produced by stereoselective hydroxylation of the natural product compactin. We report here the metabolic reprogramming of the antibiotics producer Penicillium chrysogenum toward an industrial pravastatin production process. Following the successful introduction of the compactin pathway into the β-lactam-negative P.

Study on decomposition products of norbixin during bleaching with hydrogen peroxide and a peroxidase by means of UPLC-UV and mass spectrometry.

The decomposition products of norbixin, a component of the natural colouring agent annatto, have been studied under bleaching conditions in water and in a whey matrix. In water, several unsaturated aldehydes and ketones of carboxylic acids were identified with UPLC-UV/MS and high resolution mass spectrometry techniques. Based on these products a reaction scheme for the decomposition of norbixin is proposed.

Polychlorinated Biphenyls, Dibenzo-p-dioxins, and Dibenzofurans in Harbor Porpoises (Phocoena phocoena) Stranded on the Dutch Coast Between 1990 and 1993.

Congener-specific polychlorinated biphenyl (PCB) concentrations were determined in the blubber, kidney, and liver tissues of 22 harbor porpoises (Phocoena phocoena) stranded on the Dutch coast. For comparison, the PCB concentrations in blubber and liver samples of four porpoises from the vicinity of Greenland were investigated. In ten blubber samples, the non-ortho PCB concentrations were determined, while in four of these the levels of chlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) were analyzed.