Magnetic resonance imaging verification of anterior capsular impingement in the hip joint: A three-dimensional analysis.

Background: This study aimed to clarify whether the anterior hip capsular ligament is impinged between the acetabulum and femur during hip flexion or adduction and to determine the difference in the distance between the femur and capsular ligament in healthy adults and those with hip pain.

Methods: Magnetic resonance imaging of the hip joint was conducted at the following hip positions: 0° of flexion, 60° of flexion, maximal flexion, and maximal flexion with adduction. A three-dimensional model of the capsular ligament and femur was constructed.

Fall assessment in healthy older adults: Approach using rambling-trembling decomposition method.

Background: This study explored useful indices of potential fall risk in healthy older adults based on comprehensive clinical and simple quantitative posturographic measurements.

Methods: A total of 64 community-dwelling older adults aged ≥65 years were classified into fallers and non-fallers based on previous fall history. After excluding two participants due to missing data, 16 and 46 participants were included in the faller and non-faller groups, respectively.

An assessment of the autotrophic/heterotrophic synergism in microalgae under mixotrophic mode and its contribution in high-rate phosphate recovery from wastewater.

Dual carbon metabolisms and the synergism contribute to improving nutrient recovery under mixotrophy. However, how synergism influences nutrient recovery has yet to be understood, which is revealed in the current study. Due to dual carbon metabolisms and synergism,the PO-P recovery rate under mixotrophy reached 0.

New Secondary Metabolites of Mangrove-Associated Strains.

Positioned at the dynamic interface between terrestrial and marine realms, mangroves embody a vibrant tapestry of biodiversity, encompassing an array of plants, animals, and microorganisms. These microbial inhabitants of mangrove habitats have emerged as a pivotal resource for antimicrobials and a plethora of pharmaceutically valuable compounds, spanning enzymes, antineoplastic agents, pesticides, immunosuppressants, and immunomodulators. This review delves into the recent landscape (January 2021 to May 2024, according to the time of publication) of novel secondary metabolites isolated from mangrove-associated microorganisms, analyzing 41 microbial strains that collectively yielded 165 distinct compounds.

ACL reconstruction combined with anterolateral structures reconstruction for treating ACL rupture and knee injuries: a finite element analysis.

The biomechanical indication for combining anterolateral structures reconstruction (ASLR) with ACL reconstruction (ACLR) to reduce pivot shift in the knee remains unclear. This study aims to investigate knee functionality after ACL rupture with different combinations of injuries, and to compare the effectiveness of ALSR with ACLR for treating these injuries. A validated finite element model of a human cadaveric knee was used to simulate pivot shift tests on the joint in different states, including 1) an intact knee; 2) after isolated ACL rupture; 3) after ACL rupture combined with different knee injuries or defect, including a posterior tibial slope (PTS) of 20°, an injury to the anterolateral structures (ALS) and an injury to the posterior meniscotibial ligament of the lateral meniscus (LP); 4) after treating the different injuries using isolated ACLR; v.

Recent Progress in Free Radical Transformations of Allenamides.

Allenamides are special allenes, and the unique reactivity, selectivity (both stereoselective and regionally selective) and stability of allenamides have been widely studied. In this review, the development of the free radical transformation of allenamides over the last few years will be summarized. This review discusses in detail in three parts: intermolecular radical addition to C- X (X = N, S, O, Se) bonds, metal salt mediated cyclization of allenamides, and photocatalytic cyclization of allenamides.

Effects of High-Velocity Versus Low-Velocity Resistance Training on Muscle Echo Intensity in Healthy Young Women: A Randomized Controlled Trial.

Background: Improving muscle quality to prevent and treat muscle dysfunction is critical. However, effective measures to improve muscle quality remain poorly understood. We investigated the effects of high- and low-velocity resistance training (RT) on muscle quality, mass, and function before and after an 8-week intervention.

Intramuscular fat infiltration influences mechanical properties during muscle contraction in older women.

Although evidence suggests that intramuscular fat infiltration may influence muscle strength, the precise mechanisms remain unclear. This study aimed to determine whether intramuscular fat infiltration affects muscle mechanical properties during contraction and whether these mechanical properties mediate the relationship between intramuscular fat infiltration and muscle strength. Seventy-nine healthy older women aged 75.

Enhancing environmental sustainability in transferred farmlands through rural e-commerce: insights from China.

The issue of farmers neglecting environmental concerns in transferred farmlands poses a serious challenge, contradicting the long-term ecological goals of establishing resource-efficient and environment-friendly agriculture. Amidst the pivotal trend of moderately scaled agricultural operations, rural e-commerce holds promise as a catalyst and driving force for enhancing long-term environmental governance of transferred lands. The effectiveness and mechanisms of this potential, however, remain to be empirically examined.

Magnetic Resonance Images Segmentation of Multifidus based on Dense-unet and Superpixel.

Background: Lumbar disc herniation (LDH) is a common clinical condition causing lower back and leg pain. Accurate segmentation of the lumbar discs is crucial for assessing and diagnosing LDH. Magnetic resonance imaging (MRI) can reveal the condition of articular cartilage.

Spatial distribution characteristics of perfluoroalkyl substances in bulk and grain size fractionated sediments in Shenzhen Bay.

Understanding Perfluoroalkyl substances (PFASs) spatial distribution in natural environments is crucial due to their environmental persistence and potential bioaccumulation. However, limited research has investigated PFASs spatial distribution at a high resolution, especially in the Guangdong-Hong Kong-Macao Greater Bay Area. Here, we examined the composition and concentration of PFASs in 36 bulk surface sediments and grain-size fractionated sediments from 9 representative sites to determine the spatial distribution characteristics in Shenzhen Bay.

Factors influencing surgical choice and anxiety in patients with pulmonary nodules smaller than 8 mm.

Background: The detection of pulmonary nodules significantly impacts the lives and mental health of patients. Although the 2020 National Comprehensive Cancer Network (NCCN) guidelines recommend scheduled surveillance for nodules ≤8 mm, patients often opt to have their nodules surgically removed.

Methods: A cross-sectional questionnaire was administered to patients with small pulmonary nodules who presented to a local grade 3 hospital with small pulmonary nodules and decided to receive surgery versus prescribed monitoring.

Age-related change in gait efficacy and predictors of its decline: A 3-year longitudinal study.

Aim: This study aimed to calculate the minimal clinically important difference (MCID) for a modified Gait Efficacy Scale (mGES) over 3 years and to clarify the predictors of mGES decline.

Methods: In total, 87 community-dwelling older adults were enrolled in this 3-year longitudinal study. The mGES, fall history and physical function (chair stand frequency, open-eyes one-leg stand, open-close stepping test, walking speed, walking endurance [shuttle stamina walk test] and physical activity) were assessed at baseline.

PFKP confers chemoresistance by upregulating ABCC2 transporter in non-small cell lung cancer.

Background: Chemoresistance is a significant factor contributing to tumor recurrence and treatment failure in non-small cell lung cancer (NSCLC). The phosphofructokinase, platelet (PFKP) is highly expressed in NSCLC and is associated with a poor prognosis. Exploring the molecular mechanism and identifying effective strategies to overcome chemoresistance will have important clinical significance in improving the diagnosis and treatment of NSCLC.

A Cadaveric Study of the Optimal Isometric Region on the Anterolateral Surface of the Knee in Anterolateral Ligament Reconstruction.

Objective: Isolated intra-articular anterior cruciate ligament (ACL) reconstruction is not capable of restoring instability in many cases leading some to recommend concomitant anterolateral ligament (ALL) reconstruction. The satisfactory fixation site and graft length change are crucial in ligament reconstruction to restore the ALL function and avoid some unwanted graft behavior. The purpose of this investigation is to determine the optimal isometric region on the anterolateral aspect of the knee for ALL reconstruction using a three-dimensional optical instrument and a suture similar to an intraoperative isometric test.

Comparative study on the clinical efficacy of small plate assisted anatomic plate and traditional double plate in the treatment of Rüedi and Allgöwer II - III pilon fracture.

Objective: The aim of this study was to investigate the clinical efficacy of small plate assisted anatomical plate and traditional double plate in the treatment of Rüedi and Allgöwer II - III pilon fracture.

Methods And Materials: The data of 68 patients with pilon fracture admitted to Hospital from June 2017 to June 2020 were retrospectively analyzed. Study group and control group were divided according to different operation methods, with 34 cases in each group.

Research on robust fuzzy logic sliding mode control of Two-DOF intelligent underwater manipulators.

This study investigates the independent motion control of a two-degree-of-freedom (Two-DOF) intelligent underwater manipulator. The dynamics model of two-DOF manipulators in an underwater environment is proposed by combining Lagrange's equation and Morison's empirical formulation. Disturbing factors such as water resistance moments, additional mass force moments and buoyancy forces on the intelligent underwater manipulator are calculated exactly.

Luteolin-loaded biocomposites containing tantalum and polyimide with antibacterial effects for facilitating osteogenic differentiation and bone bonding.

Polymer-based composites are considered promising candidates for bone repair as they possess some outstanding advantages over ceramic/metallic/polymeric biomaterials. Tantalum (Ta)/polyimide (PI) biocomposites (PT) containing 20 v% (PT20) and 40 v% (PT40) Ta nanoparticles were fabricated, and luteolin (LU) was loaded on PT40 (LUPT40). Compared with PT20 and PI, PT40 with a high Ta content displayed high surface behaviors (, roughness, surface energy, and hydrophilicity).

Computerized tertiary lymphoid structures density on H&E-images is a prognostic biomarker in resectable lung adenocarcinoma.

The increased amount of tertiary lymphoid structures (TLSs) is associated with a favorable prognosis in patients with lung adenocarcinoma (LUAD). However, evaluating TLSs manually is an experience-dependent and time-consuming process, which limits its clinical application. In this multi-center study, we developed an automated computational workflow for quantifying the TLS density in the tumor region of routine hematoxylin and eosin (H&E)-stained whole-slide images (WSIs).

Temporal variation of per- and polyfluoroalkyl substances (PFASs) abundances in Shenzhen Bay sediments over past 65 years.

We examined the vertical distribution of per- and polyfluoroalkyl substances (PFASs) and total organic carbon in sediment cores located in Shenzhen Bay area. We investigated the Pb specific activity of the sediments and calculated the flux of PFASs to understand the temporal variation of PFASs in the past 65 years. The results showed that the concentrations of PFASs generally decreased with depth, ranging from 13 to 251 pg/g dw.

Two new species in (Ancylistaceae, Entomophthorales) from China, with a proposal for a new combination.

A taxonomic revision of s.l. (Ancylistaceae, Entomophthorales) delimited all members that form capilliconidia into the genus .

Risk factors for self-reported medication adherence in community-dwelling older patients with multimorbidity and polypharmacy: a multicenter cross-sectional study.

Background: Medication nonadherence is a significant public health problem as it contributes to poor clinical outcomes and increased healthcare costs. Older patients with multimorbidity and polypharmacy often have low medication adherence. These patients also have a high prevalence of potentially inappropriate medication (PIM) use.

Body mass index combined with (waist + hip)/height accurately screened for normal-weight obesity in Chinese young adults.

Objectives: Only a few studies have explored the prevalence of normal-weight obesity in young adults or the development of a simple evaluation index for body fat percentage. Therefore, this study aimed to examine the prevalence of normal-weight obesity in young Chinese adults and use anthropometric measurements to develop an evaluation index.

Methods: In total, 1322 college students participated in the study and were divided into the normal-weight lean, normal-weight obese, and overweight and obese groups based on their body mass index and body fat percentage.

Impact of COVID-19 pandemic on acute pancreatitis presentations, management, and in-hospital outcomes: a single-center, retrospective observational study from the northeast of China.

Background: Since initially detected in late December 2019, the novel coronavirus disease 2019 (COVID-19) outbreak rapidly swept the world, which has profoundly affected healthcare system and clinical practice in the management of gastrointestinal diseases.

Objectives: We aimed to evaluate the impact of COVID-19 pandemic on the pattern of hospital admissions and healthcare services for acute pancreatitis (AP).

Design: We conducted a retrospective observational cohort study using the anonymized electronic medical records.