Adsorption-desorption of propyrisulfuron in six typical agricultural soils of China: kinetics, thermodynamics, influence of 38 environmental factors and its mechanisms.

Propyrisulfuron, a novel sulfonylurea herbicide, effectively suppresses intracellular acetolactate synthase activity for weed control, but its adsorption behavior in the soil environment remains unclear. To assess potential agroecosystem risks, the adsorption-desorption behavior and mechanism of propyrisulfuron in six typical agricultural soils of China were investigated using a batch equilibrium method, Density Functional Theory (DFT), Fourier Transform Infrared Spectroscopy (FTIR), and Scanning Electron Microscopy equipped with Energy Dispersive X-ray (SEM-EDX) techniques. It is indicated that the adsorption-desorption of propyrisulfuron in six soils reached equilibrium at 36 hours under the optimum water-to-soil ratio (WSr) of 5:1.

The effects of neurofeedback training on behavior and brain functional networks in children with autism spectrum disorder.

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with an unclear pathogenesis to date. Neurofeedback (NFB) had shown therapeutic effects in patients with ASD. In this study,we analyzed the brain functional networks of children with ASD and investigated the impact of NFB targeting the beta rhythm training on these networks.

Enzymatic Regulation of the Gut Microbiota: Mechanisms and Implications for Host Health.

The gut microbiota, a complex ecosystem, is vital to host health as it aids digestion, modulates the immune system, influences metabolism, and interacts with the brain-gut axis. Various factors influence the composition of this microbiota. Enzymes, as essential catalysts, actively participate in biochemical reactions that have an impact on the gut microbial community, affecting both the microorganisms and the gut environment.

Causal relationship between serum uric acid levels and male infertility: a bidirectional two-sample Mendelian randomization study.

Background: Uric acid is the final metabolic product of purines in the human body and has been implicated in the pathogenesis of various diseases. Nevertheless, the relationship between serum uric acid levels and male infertility remains inconclusive. This Mendelian randomization (MR) study aims to elucidate the potential impact of serum uric acid levels on the risk of male infertility.

Oxidative stress controls lncRNA-mediated sow granulosa cell functions in a FoxO1-dependent manner.

Background: Oxidative stress (OS) is involved in low female fertility by altering multi-omics such as the transcriptome, miRome, and lncRNome in follicular cells and follicular fluid. However, the mechanism by which OS affects multi-omics dynamics remains largely unknown. Here, we report that OS induces lncRNome dynamics in sow granulosa cells (sGCs), which is partially dependent on the transcription factor activity of its effector, FoxO1.

Dielectric barrier discharge-mediated one-pot rapid synthesis of platinum nanoclusters for fluorescent sensing of malachite green.

A one-pot method using a dielectric barrier discharge microplasma reactor was employed to rapidly and conveniently prepare glutathione-protected platinum nanoclusters (GSH@PtNCs) with green fluorescence emission. Based on the inner filter effect (IFE), the synthesized GSH@PtNCs were utilized to achieve fast, sensitive and selective detection of malachite green.

Preparation of diacylglycerol by lipase-catalyzed glycerolysis in the presence of polar adsorption materials.

Diacylglycerol (DAG) is a functional oil used extensively in various industries. Glycerolysis of a natural oil with glycerol was widely employed for DAG preparation. Numerous studies have demonstrated that glycerol in the reaction affects lipase performance.

Mining of latent feruloyl esterase resources in rumen and insight into dual-functional feruloyl esterase-xylanase from Pecoramyces ruminantium F1.

Feruloyl esterase (FAE) has been extensively studied for its crucial auxiliary effect in the biodegradation of lignocellulose. In this study, a FAE database including 15,293 amino acid sequences was established to gain a better understanding of rumen FAEs through multi-omics analysis. The higher expression level of rumen fungal FAEs over bacterial FAEs suggests that rumen fungi may have more important role in the lignocellulose degradation.

Mild defluorinative -acrylation of amines with (trifluoromethyl)alkenes: synthesis of α-arylacrylamides.

A practical and efficient method for the -acrylation of amines with (trifluoromethyl)alkenes is achieved the cleavage of three C(sp)-F bonds, affording a diverse range of useful tertiary and secondary α-arylacrylamides in high yields. This protocol features mild conditions, is transition-metal free, operationally simple, gram-scalable, and compatible with valuable functional groups, and has a broad substrate scope. Mechanistic studies indicate that exchange of an oxygen atom happens between HO and NaOH, and that the oxygen atom is incorporated into the α-arylacrylamides the -defluorooxylation of the (trifluoromethyl)alkene.

Evolutionary Analysis and Catalytic Function of LOG Proteins in Plants.

Background: The plant hormone cytokinin is a conserved regulator of plant development. LONELY GUY (LOG) proteins are pivotal in cytokinin biosynthesis. However, their origin, evolutionary history, and enzymatic characteristics remain largely uncharacterized.

1-Deoxynojirimycin Derivative Containing Tegafur Induced HCT-116 Cell Apoptosis through Mitochondrial Dysfunction and Oxidative Stress Pathway.

Three 1-deoxynojirimycin (DNJ) derivatives (named -) including DNJ and tegafur (TGF) were designed and synthesized, and their antiproliferative effects were investigated. -, especially , exerted good lipophilicity, α-glucosidase inhibitory activity, and antitumor effects. Mechanism studies indicated that significantly induced cell apoptosis and S-phase block and inhibited migration of HCT-116 cells.

Probiotics in piglet: from gut health to pathogen defense mechanisms.

Various problems and obstacles are encountered during pig farming, especially the weaning phase when switching from liquid to solid feed. Infection by pathogenic bacteria causes damage to the intestinal barrier function of piglets, disrupts the balance of the intestinal microbiota, and destroys the chemical, mechanical, and immune barriers of the intestinal tract, which is one of the main causes of gut inflammation or gut diseases in piglets. The traditional method is to add antibiotics to piglet diets to prevent bacterial infections.

Rumen-Targeted Mining of Enzymes for Bioenergy Production.

Second-generation biofuel production, which aims to convert lignocellulose to liquid transportation fuels, could be transformative in worldwide energy portfolios. A bottleneck impeding its large-scale deployment is conversion of the target polysaccharides in lignocellulose to their unit sugars for microbial fermentation to the desired fuels. Cellulose and hemicellulose, the two major polysaccharides in lignocellulose, are complex in nature, and their interactions with pectin and lignin further increase their recalcitrance to depolymerization.

Intrafibrillar calcium carbonate mineralization of electrospinning polyvinyl alcohol/collagen films with improved mechanical and bioactive properties.

Collagen films play an essential role in guided bone-regeneration (GBR) techniques, which create space, promote cell adhesion, and induce osteogenic differentiation. It is therefore crucial to design appropriate GBR films to facilitate bone regeneration. However, current electrospun collagen scaffolds used as bioactive materials have limited clinical applications due to their poor mechanical properties.

Dynamic atlas of histone modifications and gene regulatory networks in endosperm of bread wheat.

Dissecting the genetic basis of seed traits in wheat is impeded by limited genetic polymorphisms and significant variations caused by environmental conditions and seed position in a spikelet. Seed performance is largely determined by endosperm development controlled by spatiotemporal variation in gene activities, which is greatly affected by chromatin status. Here, we map genome-wide dynamic distributions of H3K27me3, H3K4me3 and H3K9ac modifications and profile gene transcription across wheat endosperm development.

Development and Validation of a Predictive Model for Maternal Cardiovascular Morbidity Events in Patients With Hypertensive Disorders of Pregnancy.

Background: Hypertensive disorders of pregnancy (HDP) are a major contributor to maternal morbidity, mortality, and accelerated cardiovascular (CV) disease. Comorbid conditions are likely important predictors of CV risk in pregnant people. Currently, there is no way to predict which people with HDP are at risk of acute CV complications.

VEGFB ameliorates insulin resistance in NAFLD via the PI3K/AKT signal pathway.

Background: Non-alcoholic fatty liver disease (NAFLD) is one of the most universal liver diseases with complicated pathogenesis throughout the world. Insulin resistance is a leading risk factor that contributes to the development of NAFLD. Vascular endothelial growth factor B (VEGFB) was described by researchers as contributing to regulating lipid metabolic disorders.

Seawater alkalization via an energy-efficient electrochemical process for CO capture.

Electrochemical pH-swing strategies offer a promising avenue for cost-effective and energy-efficient carbon dioxide (CO) capture, surpassing the traditional thermally activated processes and humidity-sensitive techniques. The concept of elevating seawater's alkalinity for scalable CO capture without introducing additional chemical as reactant is particularly intriguing due to its minimal environmental impact. However, current commercial plants like chlor-alkali process or water electrolysis demand high thermodynamic voltages of 2.

A hovering bubble with a spontaneous horizontal oscillation.

Active matters, characterized by multi-mode motions, have been emerging for both engineering and biological applications. Generally, active objects rely on the symmetry-broken structures, compositions, or interfacial activities through a physical or chemical approach. Here, we report an active bubble spontaneously hovering with a horizontal oscillation at the solid/liquid interface by impacting a stationary laser beam into a liquid through a transparent solid cover.