Publications by authors named "Yun-Sun"

Current guidelines recommend a two-step algorithm rather than relying solely on a single test for diagnosing infection. This algorithm starts with enzyme immunoassay (EIA) for detecting glutamate dehydrogenase (GDH) and toxins A/B, followed by nucleic acid amplification test (NAAT) for GDH-positive but toxin-negative cases. This study compared the performance of three commercial NAATs: the STANDARD M10 , Xpert , and BD MAX Cdiff assays, utilized as confirmatory testing of the two-step algorithm.

View Article and Find Full Text PDF
Article Synopsis
  • Understanding the phenotypes and endotypes of atopic dermatitis (AD) is crucial for creating tailored treatments, and recent research highlights the connection between gut health and skin conditions.
  • The study analyzed data from a large cohort of children to identify five distinct AD phenotypes and their risk factors, particularly focusing on the early-onset persistent and late-onset types.
  • Multiomics analyses revealed specific gut microbiome and metabolic characteristics associated with these phenotypes, suggesting that early-life gut health may influence the development and severity of AD in children.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to identify factors contributing to job stress in pediatric nurses, focusing on fatigue levels and their relationships with parents of patients.
  • Participants included pediatric nurses with at least 6 months of experience, recruited from various hospital units, using self-report questionnaires for data collection and analysis.
  • Results revealed that fatigue significantly correlates with job stress, with younger nurses experiencing less stress than their older counterparts, highlighting the need for support strategies to manage fatigue and reduce stress, especially during challenging times like the COVID-19 pandemic.
View Article and Find Full Text PDF

This study compared the performance of two commercial molecular assays, the STANDARD M10 assay (M10) and the Xpert assay (Xpert), for detecting toxigenic in stool specimens. A total of 487 consecutive stool specimens submitted for routine testing between June and November 2023 were included. Following routine testing using C.

View Article and Find Full Text PDF

Background: Gender sensitivity, which is the capacity to recognize and address issues of gender discrimination and inequality, is initiated with an awareness of gender differences. This is particularly crucial in nursing, where care is tailored to the holistic needs of individuals. Given the sensitive nature of nursing to gender variances, it is essential that the influences of nurses' own experiences and perceptions on their gender sensitivity are explored.

View Article and Find Full Text PDF
Article Synopsis
  • This study evaluated the performance of the new SMG HHV-6 Q Real-Time PCR Kit compared to the existing RealStar HHV-6 PCR Kit, focusing on factors like sensitivity, specificity, and analytical precision.
  • The SMG assay showed a high limit of detection for both HHV-6A and HHV-6B DNA, with excellent linearity and low variability in results across different tests.
  • Clinical performance analysis indicated that the SMG kit is a reliable and sensitive method for accurately detecting and distinguishing between HHV-6A and HHV-6B DNA, outperforming RealStar in some metrics.
View Article and Find Full Text PDF

Aroma is an important factor affecting the quality of tea. Fatty acids are one of precursors and their derived contributes to tea aroma considerably. In this study, we analyzed the fatty acids of Jinmudan fresh tea leaves in different stalk position.

View Article and Find Full Text PDF
Article Synopsis
  • The study examines challenges in sample preparation for COVID-19 testing, specifically focusing on the real-time reverse transcription polymerase chain reaction (rRT-PCR) method, which can be time-consuming and labor-intensive.
  • Researchers explored different extraction-free protocols that combined heat treatment, sample dilution, and the use of Proteinase K and RNase inhibitors, validating their effectiveness with both positive and negative clinical samples.
  • Results showed that combining sample dilution with heat treatment yielded the highest sensitivity for detecting SARS-CoV-2, indicating that optimizing sample conditions can improve diagnostic testing efficiency and sustainability.
View Article and Find Full Text PDF
Article Synopsis
  • A study compared the effectiveness of two stool antigen tests, STANDARD F and SD BIOLINE, in diagnosing Helicobacter pylori infection among 335 patients.
  • STANDARD F showed a sensitivity of 95.6% and specificity of 94%, while SD BIOLINE had a sensitivity of 92.6% and specificity of 93.5%.
  • The results indicate that STANDARD F performs similarly to SD BIOLINE, making it a reliable option for detecting H. pylori infection.
View Article and Find Full Text PDF

Purpose: Based on the World Health Organization framework on reproductive health, this descriptive correlational study investigated the factors affecting reproductive health-promoting behaviors ofmarried women, with a focus on family values and reproductive health knowledge.

Methods: A cross-sectional survey was conducted on 170 married women between the ages of 25and 49 years living in Daegu, Korea. The general and reproductive health characteristics, family values, and reproductive health knowledge of married women were identified, as well as factors affecting reproductive health-promoting behaviors.

View Article and Find Full Text PDF

In order to develop a therapeutic target for T cells, it is necessary to amplify T cells and increase activity through antigen-presenting cells (APCs) expressing an intracellular cancer antigen. Although dendritic cells are frequently used as APCs, producing dendritic cells is costly and time-consuming. In addition, as dendritic cells are attached cells, they are not suitable for mass production for use as immune cell therapy.

View Article and Find Full Text PDF

Climate change has become one of the highlighted issues of the world, resulting in vulnerability and adverse effects on livelihoods. It leads to an undeniable challenge for policymakers, the government, and other respective associations to formulate effective strategies; however, before formulating any coping, adaptation, or mitigation strategies, understanding the reality and perception of local people is crucial. This study investigated whether local farmers inhabiting Lower Mustang are aware of climatic change.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluated the effectiveness of the STANDARD F S. pneumoniae antigen test against the BinaxNOW S. pneumoniae antigen card using 206 urine samples.
  • Results showed that the performance of the STANDARD F test was very similar to that of the BinaxNOW test.
  • The findings suggest that the STANDARD F assay could be a useful option for diagnosing invasive pneumococcal disease.
View Article and Find Full Text PDF
Article Synopsis
  • The study examined the effectiveness of the PowerChek SARS-CoV-2 and Influenza A & B Multiplex Real-time PCR Kit compared to BioFire Respiratory Panels 2 and 2.1 using 147 nasopharyngeal swab samples.
  • The limit of detection (LOD) for the PowerChek kit was found to be very sensitive for all viruses tested, with specific values for SARS-CoV-2, influenza A, and B.
  • The PowerChek assay showed high accuracy with positive and negative agreement rates of 97.5% and 100% for SARS-CoV-2, and 100% for both influenza A and B, indicating it could be a reliable tool for diagnosing
View Article and Find Full Text PDF

Signal transducer and activator of transcription 3 (STAT3) plays a critical role in the formation and growth of human cancer. Therefore, STAT3 is a therapeutic target for cancer drug discovery. Acacetin, a flavone present in various plants, inhibits constitutive and inducible STAT3 activation in STAT3-activated DU145 prostate cancer cells.

View Article and Find Full Text PDF
Article Synopsis
  • Researchers used whole-genome sequencing (WGS) to analyze an O63:H6 strain from a child with hemolytic uremic syndrome and compared it with other strains in databases.
  • The findings indicated that the strain was genetically similar to EHEC, despite missing some genes, and suggested that WGS could effectively differentiate between EHEC strains that have lost toxin genes (EHEC-LST) and EPEC in routine lab diagnostics.
View Article and Find Full Text PDF
Article Synopsis
  • - The study evaluates the effectiveness of the PowerChek Multiplex Real-time PCR Kit in detecting SARS-CoV-2, influenza A & B, and RSV simultaneously, compared to another test called BioFire Respiratory Panel 2.1 (RP2.1).
  • - Results showed a perfect agreement of 100% for detecting SARS-CoV-2 and influenza viruses, with slightly lower but still high accuracy for RSV detection.
  • - The assay shows promising sensitivity and accuracy, indicating its potential as a useful tool for diagnosing infections when these viruses are circulating together in healthcare settings.
View Article and Find Full Text PDF

Purpose: Granular corneal dystrophy type 2 (GCD2) is an autosomal dominant disorder and is associated with the arginine to histidine substitution at codon 124 (p.R124H) of the gene. Although p.

View Article and Find Full Text PDF
Article Synopsis
  • * Whole exome sequencing was conducted on 13 NTM-LD patients suspected of having PCD, identifying varying variants related to the disorder.
  • * Results revealed that about 30.8% of patients had two harmful genetic variants associated with PCD, suggesting a significant genetic component in those with NTM-LD who show PCD symptoms.
View Article and Find Full Text PDF

Two-dimensional (2D) transition metal dichalcogenides (TMDs) have attracted significant attention for their outstanding optoelectrical properties. Unlike most TMDs with layer-dependent photoresponsivity, rhenium disulfide (ReS) shows excellent thickness-independent photoresponsivity. Herein, we show a surfactant-free polyvinyl alcohol (PVA)-assisted exfoliation method for 2D-TMDs in aqueous solution and a transparent photosensitive memristor synapse device based on ReS nanosheets composited with PVA.

View Article and Find Full Text PDF

Ethnopharmacological Relevance: Huangkui capsule (HKC), extracted from Abelmoschus manihot (L.) medic (AM), as a patent proprietary Chinese medicine on the market for approximately 20 years, has been clinically used to treat chronic glomerulonephritis. Renal fibrosis has been implicated in the onset and development of diabetic nephropathy (DN).

View Article and Find Full Text PDF
Article Synopsis
  • The study assessed the MicroIDSys Elite system, a new mass spectrometry tool, for identifying mycobacteria in positive MGIT cultures.
  • It tested the system's accuracy with 63 reference strains and 167 primary and subcultured mycobacterial samples, achieving 85.6% and 95.2% identification rates, respectively.
  • The results suggest that the MicroIDSys Elite system is an effective diagnostic tool for routine identification of mycobacterial species in liquid cultures.
View Article and Find Full Text PDF
Article Synopsis
  • The AFIAS-Rota and AFIAS-Noro assays are new diagnostic tests for detecting rotavirus and norovirus infections, respectively, developed by Boditech Med Inc.
  • Performance evaluation involved comparing these assays with RIDASCREEN ELISA kits using clinical stool samples, with multiplex real-time PCR as the reference method, during a study period from November 2018 to January 2019.
  • Results showed the AFIAS assays had excellent agreement with RIDASCREEN tests and demonstrated short turnaround times, making them a convenient option for rapid initial screening, despite lower sensitivity in detecting norovirus.
View Article and Find Full Text PDF

With the development of the Internet of Things (IoT), indoor photovoltaics are attracting considerable interest owing to their potential to benefit various IoT-related fields. Therefore, this study investigates the use of transparent hydrogenated amorphous silicon (a-Si:H) solar cells for a broad range of applications, including indoor light harvesting. High-gap triple layers were employed in the a-Si:H solar cells to obtain a high shunt resistance and high short-circuit current, , and open-circuit voltage, , under indoor illumination.

View Article and Find Full Text PDF